Sorry to be off-topic, but I was drawn to the story because of the McMaster reference and I bet some other Hamiltonians probably will be to. Would love to connect with any HN folks in Hamilton!
McMaster researchers may have found a way to restore metabolism to youth levels
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Re: McMaster researchers may have found a way to restore metabolism to youth levels
#22So, I thought serotonin was basically the "happiness" hormone. Wouldn't inhibiting serotonin have side-effects like making them feel depressed or at least less happy? Can any biologists comment? EDIT: as a replier mentioned, it's discussed in the article.
That's pop-neuro-psych gibberish marketing talk--molecules aren't moods any more than motor oil is velocity. Also, synaptic serotonin is in a different compartment. But I was pondering about the link between SSRIs and weight gain.
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#23Seems like we are trying to engineer a solution that is fundamentally a behavioral issue rather than mechanical. I do realize though that assuming we can reign in consumption socially is a non-starter at the same time though I think enabling high levels of consumption is the opposite of what we should be doing. That said, anything we can do to reverse aging I am all for, I just hope our consumption patterns can becom…
It's still going to require effort, for many people, to maintain a healthy weight and exercise enough. But it's hard enough to do that as it is; if you can turn off a defect that causes the body to pile on unneeded pounds of fat (that interfere with health, mood, and the ability to exercise) with age, then you should.
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#24Seems like we are trying to engineer a solution that is fundamentally a behavioral issue rather than mechanical. I do realize though that assuming we can reign in consumption socially is a non-starter at the same time though I think enabling high levels of consumption is the opposite of what we should be doing. That said, anything we can do to reverse aging I am all for, I just hope our consumption patterns can becom…
Isn't the change in metabolism as you age mechanical?
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#25Sorry to be off-topic, but I was drawn to the story because of the McMaster reference and I bet some other Hamiltonians probably will be to. Would love to connect with any HN folks in Hamilton!
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#26Using a decarboxylase or AADC[0] inhibitor like EGCG[1] found in green tea extract limits peripheral serotonin metabolism, especially if you're supplementing with serotonin precursors like tryptophan or 5-HTP to avoid heart-valve issues.[2]
See Examine.com's note in the 5-HTP article[3] and the associated citation.[4] 800mg of EGCG 2 hours prior to supplementation demonstrated decarboxylase inhibition.
[0] http://en.wikipedia.org/wiki/Aromatic_L-amino_acid_decarboxy...
[1] http://www.amazon.com/gp/product/B000MYW2ZA/
[2] http://www.ncbi.nlm.nih.gov/pubmed/15781732
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#27Sorry to be off-topic, but I was drawn to the story because of the McMaster reference and I bet some other Hamiltonians probably will be to. Would love to connect with any HN folks in Hamilton!
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#28Re: McMaster researchers may have found a way to restore metabolism to youth levels
#29Sorry to be off-topic, but I was drawn to the story because of the McMaster reference and I bet some other Hamiltonians probably will be to. Would love to connect with any HN folks in Hamilton!
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#30Sorry to be off-topic, but I was drawn to the story because of the McMaster reference and I bet some other Hamiltonians probably will be to. Would love to connect with any HN folks in Hamilton!