First off: I'm very pleased to see that YC are backing startup concepts
other than an endless stream of privacy-invading "social" surveilices, games, and new forms of intrusive and annoying advertising. I'd posted something of a rant on that subject about 7 months ago which didn't go over hugely at the time:
https://news.ycombinator.com/item?id=7063690
Secondly: this is actually what I'd consider a "Big Problems" start-up, a field which has been notoriously hard to crack. Kleiner Perkins' failure in cleantech over the past 7 year or so has been humbling.
https://news.ycombinator.com/item?id=6906635
But that said: nuclear's got quite a few issues with it, most particularly the abundance of fuel, and long-term safety.
Outside a 6-80 year window in which existing reserves would last (the low-end estimate is "run everything on nuclear", the high is "continue with modest growth at present levels of energy output"), where and/or whether there's enough uranium, plutonium, or thorium to provide energy over the long term is a very real concern.
Even beyond that is the safety profile in a world in which a large fraction of human energy production is derived from nuclear power. If _present_ electrical generation needs were to be met, the number of reactors required would grow from the present TK to over 15,000. With a lifetime of 40 years, plus ten years for construction, and 20 for decommissioning, you're looking at bringing a new reactor online, and an old reactor offline, every day. At any given time there would be 3,750 rectors under construction and another 7,500 being decommissioned. Given the US NRC's estimates of 125 paramilitary security personnel per nuclear plant, you'd nave an army, literally, of 1,875,000 security personnel (all highly vetted) worldwide. Not to mention your supply of nuclear engineers and other highly skilled staffing requirements.
See Derek Abbott's "Is Nuclear Power Globally Scalable":
http://ieeexplore.ieee.org/stamp/stamp.jsp?reload=true&arnum...
SG Collins, "Nuke Skeptic"
http://fixyt.com/watch?v=IHYpYB2vUjM
The video makes a few points, but the primary one is this: Nuclear proponents are, in their beliefs, not essentially more scientific than nuke skeptics. That they're also influenced by ideals and desires, and even persuasion. Discussions of benefits and risks are usually scoped locally: here and now. The civilization that we have right now. That's short-sighted.
I'm not fully opposed to nuclear power. But I'm exceptionally skeptical that it will serve us well in the long run.
http://www.reddit.com/r/dredmorbius/comments/2awjj2/thoughts...