Earlier quoted context omitted.
As the article noted, this isn't just a US thing and actually isn't just an A380 thing. The A380 is just a very high-profile victim of it. The problems are twofold: 1. Four-engine airliners, regardless of size, are losing, basically worldwide, to twin-engine airliners with better fuel consumption. This is why the A380 and 747-8 sales are sluggish. This is why the A340 buyback program exists (airlines can't get rid of…
The 380 makes a lot of sense in heavily congested air corridors. Anywhere in China, Japan, SE Asia...there is more demand than airports and runways, so a bigger plane will just work better. The US market is better for point to point because we have many more small airports and lots of redundant infrastructure that doesn't really need to be maximized. Europe is somewhat in the middle.
You'd think that, but the Asian carriers who've bought A380s are still mostly using them on their long-haul routes.
This is a lesson Boeing has learned twice now: once with the 747SP, and again with the proposed 787-3. Both were designed as specialized aircraft to bring efficiency to slightly shorter high-density routes. But the 747SP only had a production run of 45 aircraft, and the 787-3 was cancelled due to lack of interest. The 787-8, on the other hand, has been doing well in Asia, and several low-cost carriers fly them now.
The A380 is an even worse fit because it requires upgrading the airport infrastructure, which either won't happen or won't happen soon enough on some of the highest-density routes (as the article notes, Mumbai couldn't handle A380s until very recently).
Boeing seems to be sensitive to this with their planned folding wingtip on the 777X family, designed to guarantee that airports which can handle current 777s will be able to handle the larger 777X. It'll be interesting to see if that pans out.