Earlier quoted context omitted.
I suspect that, arguably more counter-intuitively, it will push the price up, fed by increased speculation due to apparent signs of Bitcoin "going mainstream" that will far exceed any actual Expedia transactions taking place. I'm more intrigued by the commercial decision from Expedia's perspective. Presumably they've done a back of the envelope calculation and decided "group of people more likely to pick Expedia over…
They have tabs that go "Credit card", "Paypal", "Bitcoin", so, presumably, 0 people will be confused by that, plus they have lower fees than either CC companies or Paypal, so it sounds like an obvious win for them.
There are, after all, enough people confused by a concept as non-novel as the address their credit card is registered to for some companies to be willing to pay higher interchange fees and accept higher chargeback risk to omit those fields from their CC forms.