Earlier quoted context omitted.
The fuel supply for conventional reactors is limited because they rely on U235, which is 0.7% of uranium. Fast reactors could use the rest of the uranium. That multiplies the supply by more than 100x because it means you can economically retrieve fuel from lower-grade ore, or even from seawater, which would extend the supply to millions of years. Russia has several fast reactors in production right now, and is buildi…
My understanding of seawater is that uranium concentrations are 0.01 - 0.02%, and that it's not thermodynamically feasible to extract it for energy at those concentrations.
...which says that EROI is 22 assuming a conventional reactor. Ie., we'd get 22 times as much energy out as we spent on extraction. With a fast reactor the ratio would be a hundred times better, since we could use all that uranium instead of 0.7% of it.