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Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

nature.com

1–10 of 88 posts

Re: Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

#4
The test is lab grade monkey chow vs. less lab grade monkey chow. I don't think one can extrapolate that eating less calories on a very high quality and low toxin source of calories is better.

Monkeys do best on perfectly ripe and fresh tropical fruits. Is that what they were eating? I really doubt it.

Re: Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

#5
If I'm reading this correctly it says that the findings apply to 1) short lived species and 2) rhesus primates. It also says that the effects of CR may or may not be preserved on humans.

So the only real finding here seems to be that we are now able to extend the lifespan of some monkeys.

Re: Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

#6

So if you don't eat much you may live longer. It will certainly FEEL longer.

While stated as sarcasm, this is a very reasonable concern.

Suppose we can extend human life with Calore Restriction, but at the cost of having to slow person's activity to the point that the overall amout of actions (work, leisure etc.) remains the same as during shorter, more intense life.

Would that still be worth it? What would a person gain through longer lifespan if she was limited to roughly the same amout of activity anyway? Wouldn't competing people gain advantage simply by being able to take advantage of opportunities quicker?

Re: Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

#7
Am I the only one who finds this caloric restriction stuff depressing? If starving for 50 years will increase my life I don't even want to know about it. Stupid science. Next they're going to tell us that a combination of caloric restriction & celibacy will do even more.

Re: Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

#8

The test is lab grade monkey chow vs. less lab grade monkey chow. I don't think one can extrapolate that eating less calories on a very high quality and low toxin source of calories is better. Monkeys do best on perfectly ripe and fresh tropical fruits. Is that what they were eating? I really doubt it.

Toxin is a buzzword that I use to tell when someone is easily deceived by woo-woo fake science.

The idea that anything processed in a factory is full of "toxins" and anything from nature is "healthy" is an irritating and pervasive fallacy.

Were you referring to a specific toxin that is in their foods, or were you using it in the more vague and hand-wavy "woo woo homeopathic" sense?

Re: Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

#9
post #6

So if you don't eat much you may live longer. It will certainly FEEL longer.

While stated as sarcasm, this is a very reasonable concern. Suppose we can extend human life with Calore Restriction, but at the cost of having to slow person's activity to the point that the overall amout of actions (work, leisure etc.) remains the same as during shorter, more intense life. Would that still be worth it? What would a person gain through longer lifespan if she was limited to roughly the same amout of…

I've dabbled with caloric restriction before for brief periods of time. I found that my body adjusted pretty quickly to it in a metabolic sense and the only real issue (and the reason I dabbled but never became a real adherent) was appetite, which I suspect will eventually be solvable via pharmacological means.

Intermittent caloric restriction is also showing promise. You don't have to starve yourself daily -- just a couple of times a week -- to show some of the same benefits. Perhaps not to the same degree, but far more comfortably.

Re: Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

#10

If I'm reading this correctly it says that the findings apply to 1) short lived species and 2) rhesus primates. It also says that the effects of CR may or may not be preserved on humans. So the only real finding here seems to be that we are now able to extend the lifespan of some monkeys.

Both are used as model organisms, because they are similar in many ways to humans. If both mice and animals show the same result, it is reasonable to expect that it may also occur in humans. Obviously this would need to be tested before any definite conclusions can be reached, and that is going to take a long time.
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