In general or with regards to April Fool's?
In general, the same way it's always done: years of social activism, patient stating and re-stating of your case to an uncaring public who is barely impacted by your position, possible civil disobedience (though I have no idea what form that would take in this context... Being told by our employer to roll out an April Fool's project and responding "No, it's a waste of our time and our customers' time, I'm not doing it" perhaps).
With regards to April Fool's: I wouldn't bother. It's a once-a-year annoyance, not nearly as disruptive as Christmas. If your goal is to encourage people to knock off nonsense, than I'd easily start with the pagan-holiday-cum-Christian-nativity-celebration-cum-marketing-extravaganza that we hold every December; it's far more disruptive to the economy and people's psychological well-being.
If you find April Fool's too annoying, take a personal day and tune out; go read a book, go on a walk, take the disruption of functional communication on the Internet as an opportunity to step back from the Internet. Use the opportunity to look around at the world outside the screen and see what needs improvement; maybe you'll come back on April 2nd inspired.