Earlier quoted context omitted.
I got up to 9,000 with: left, down, right, down, (repeat)
Not bad. My new simple algo is: 1. Down until you cannot go down 2. Left 3. Down until you cannot go down 4. Right 5. Go to 1.
When I began playing I was moving around the board in an unorganized fashion, but am now finding that moving the larger numbers to one corner (bottom-right for me) is the best method. By having your block consolidation take place in one particular area, the odds that you'll have matching large numbers goes up dramatically.