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Anti-ageing compound set for human trials after turning clock back for mice

theguardian.com

11–20 of 243 posts

Re: Anti-ageing compound set for human trials after turning clock back for mice

#11

Anyone care to explain why this is too good to be true? Because it's always too good to be true.

The discovery concerns decline in mitochondrial function with age in muscle tissue.

Another article about this, http://www.bbc.co.uk/news/health-25445748, explains that this could never be a cure-all for ageing. Other aspects such as shortening of telomeres or damage to DNA would not be reversed.

Re: Anti-ageing compound set for human trials after turning clock back for mice

#12
post #4

I always wonder about this quote, “Whether that means we’ll all live to 150, I don’t know, but the important part is that we don’t spend the last 20 to 30 years of our lives in bad health.” Imagine a process that makes you feel like you are 25 right up until you body gives up at a physical age of 100 or something. Do you end up doing riskier things because you don't "feel" old? And if you did would you die sooner? It…

I'd rather have the choice. I have no choice with ageing. The same is true of "immortality". What immortality really means is that you kind of have a choice of not disappearing forever (well unless a car runs you down or something, but in the future that can probably be fixed, too, by "backing ourselves up").

Re: Anti-ageing compound set for human trials after turning clock back for mice

#13

> "with scientists set to look at how the theory of age reversal can be used to treat diseases such as cancer, dementia and diabetes." Alzheimer's medications can generally improve cognition. Age-reversal medications might work even better if used at an early age. I always see articles, media, and papers focusing on how something new can be used to treat some existing disease. But what I'm always thinking is "can I u…

Yes. http://dresdencodak.com/2009/09/22/caveman-science-fiction/

Re: Anti-ageing compound set for human trials after turning clock back for mice

#14
post #6

Can anyone explain how this compound differs from the NAD you can buy as a supplement, if at all?

Well I do see this quote:

"Turner said a “magic pill” that reverses ageing is several years away, partially due to the cost of the compound, which would be about $50,000 a day for a human."

So in guessing there's some special processing of the compound or a special way to get it into each cell somehow.

Re: Anti-ageing compound set for human trials after turning clock back for mice

#16

> "with scientists set to look at how the theory of age reversal can be used to treat diseases such as cancer, dementia and diabetes." Alzheimer's medications can generally improve cognition. Age-reversal medications might work even better if used at an early age. I always see articles, media, and papers focusing on how something new can be used to treat some existing disease. But what I'm always thinking is "can I u…

The same is true of artificial intelligence. For example, articles always mention that brain simulation would help us understand brain diseases (alzheimer, schizophrenia, etc.) better and barely mention the much bigger implications of strong AI (like that it might be the last thing humans ever need to invent).

Re: Anti-ageing compound set for human trials after turning clock back for mice

#17
post #12
post #4

I always wonder about this quote, “Whether that means we’ll all live to 150, I don’t know, but the important part is that we don’t spend the last 20 to 30 years of our lives in bad health.” Imagine a process that makes you feel like you are 25 right up until you body gives up at a physical age of 100 or something. Do you end up doing riskier things because you don't "feel" old? And if you did would you die sooner? It…

I'd rather have the choice. I have no choice with ageing. The same is true of "immortality". What immortality really means is that you kind of have a choice of not disappearing forever (well unless a car runs you down or something, but in the future that can probably be fixed, too, by "backing ourselves up").

Rather selfish? We'll have enough problems in the coming decades with geriatric baby boomers, you now want to give people the option to live forever?

Re: Anti-ageing compound set for human trials after turning clock back for mice

#19
Great for the mice.

I don't understand this phrase "Turner said a “magic pill” that reverses ageing is several years away, partially due to the cost of the compound, which would be about $50,000 a day for a human." ?

$50,000 a day for a human ? What is the effect of a day of treatment ?

Re: Anti-ageing compound set for human trials after turning clock back for mice

#20
post #17
post #12

Earlier quoted context omitted.

I'd rather have the choice. I have no choice with ageing. The same is true of "immortality". What immortality really means is that you kind of have a choice of not disappearing forever (well unless a car runs you down or something, but in the future that can probably be fixed, too, by "backing ourselves up").

Rather selfish? We'll have enough problems in the coming decades with geriatric baby boomers, you now want to give people the option to live forever?

If they have fewer kids then where's the harm?
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