Anti-ageing compound set for human trials after turning clock back for mice

The actual paper is here, free abstract but the full PDF is paywalled: http://www.cell.com/retrieve/pii/S0092867413015213?cc=y

I always wonder about this quote,

“Whether that means we’ll all live to 150, I don’t know, but the important part is that we don’t spend the last 20 to 30 years of our lives in bad health.”

Imagine a process that makes you feel like you are 25 right up until you body gives up at a physical age of 100 or something. Do you end up doing riskier things because you don't "feel" old? And if you did would you die sooner? Its an interesting question for me. I'm not sure how that would work.

(and of course if they are successful (which I hope they are) then we're talking about pushing back retirement until 90 or maybe 95 right?)

Can anyone explain how this compound differs from the NAD you can buy as a supplement, if at all?

> "with scientists set to look at how the theory of age reversal can be used to treat diseases such as cancer, dementia and diabetes."

Alzheimer's medications can generally improve cognition. Age-reversal medications might work even better if used at an early age.

I always see articles, media, and papers focusing on how something new can be used to treat some existing disease. But what I'm always thinking is "can I use this if I don't have a disease?"

It's a strange disconnect. I know everyone is thinking what I'm thinking, but you never see this in the articles. Is it some kind of taboo?

has to happen some day, i guess