I've got 2 stories which may or may not contradict this idea:
1) I interviewed a candidate for a junior position. He seemed qualified and came with a recommendation from someone I trust. But during the interview with one of the managers in our group, he indicated that something on his resume was not accurate. He didn't directly say that, and he tried to squirm around it by saying he really meant it in this way, etc. etc. The manager took this as a big red flag that this person was not trustworthy or at least not a good match for our group. He was later told he didn't get the position. At that point he started emailing me constantly asking what he could do to get in our good graces. I had to tell him that since I wasn't the hiring manager there was nothing I could do, and that he had really blown it because it basically looked like he was lying during his interview. Now every time there's an opening in our group he emails me looking to apply for the position. This has made me 10x less likely to consider him in the future. (Granted, he didn't do his "100 hours".) But being a pest is not going to get you anywhere. Just suck it up and move on. (I wish someone had taught me how to do that when I was younger. I often got the advice, but wasn't able to implement it, much to my detriment.)
2) At an earlier job, we had a candidate apply. I thought he was pretty good, but the boss was unimpressed. During the interview I asked him if he'd read some programming books that I had found useful. He hadn't heard of them. The boss rejected him and we hired someone else. A year later we had another position. He applied again, and this time he told me he had read the books and explained how he had put some of the ideas into practice. He didn't pester us for a job and he didn't act like a psycho or a douche. He just did the hard work of learning what he was missing. We hired him. Later I left that job and started my own company and hired him again. He was a good employee and good at what he did.
I can't imagine trying to work with the guy from #1 above on a daily basis after seeing him be so persistent and annoying. I would definitely not hire #1 even if he were the most qualified candidate because of how annoying his persistence was.