I prefer the design of Python over Ruby. I'd be hard pressed to explain why -- something vague about Python being straightforward yet graceful -- but that aesthetic preference is enough to sway me.
Me too, but I don't think it's just a preference. I come from a C/C++ background (I'd say the majority of people do, or C# or Java), and Python looks much more familiar and obvious to me than Ruby. For example, this from Wikipedia: (3..6).each {|num| puts num } Has some funny brackets and pipes. In Python, it's much more familiar to C-ish folks like me: for i in range(3, 7): print i
for i in 3..6 do
puts i
end