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ADHD Pill Faces High Hurdle in Europe as Stigma Persists

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Re: ADHD Pill Faces High Hurdle in Europe as Stigma Persists

#2
I posted this in a HN thread about therapeutic uses of nicotine a week ago, but it's even more relevant here:

> A friend of mine is a psychiatrist who specializes in treating ADHD. She told me about a conference she went to recently, where someone presented an interesting paper.

> Apparently, there was an amazing study done relatively recently (last five years), in which they demonstrated that, in mice, exposure to nicotine during pregnancy results in higher rates of ADHD in the grandchildren (passed down through the female offspring exposed to nicotine in utero, not the males).

As with any study conducted on animals and not humans, there's an asterisk next to it, but these findings would be monumentally significant for understanding ADHD.

Separately, I've never understood why Adderall isn't approved for use in Europe (or, futhermore, why Vyvanse should be approved, if Adderall isn't - Vyvanse is just a more concentrated version of the d-enantiomer, making it more effective[0] and reducing the side-effects).

On an unrelated note, it looks like the copy editing on the article was a bit off. Concerta is a long-acting drug, just like Vyvanse (the article makes it seem like it isn't). Also, I'm not sure what to make of the sentence "The U.S. still dwarfs Europe in sales of ADHD drugs, but the rest of the world has been catching up."

[0] It's actually less effective by weight than Adderall XR, but that's because the mechanism it uses for the extended release is very different.

EDIT: It's interesting watching all six of the comments on here (not counting losethos's) get upvoted and downvoted in roughly equal proportions. Clearly this is a controversial topic on here; I only wish the those upvoting/downvoting would join in the discussion.

Re: ADHD Pill Faces High Hurdle in Europe as Stigma Persists

#3

I posted this in a HN thread about therapeutic uses of nicotine a week ago, but it's even more relevant here: > A friend of mine is a psychiatrist who specializes in treating ADHD. She told me about a conference she went to recently, where someone presented an interesting paper. > Apparently, there was an amazing study done relatively recently (last five years), in which they demonstrated that, in mice, exposure to n…

Of note: Adderall is by far not the only drug available for ADHD, and considering its addictive nature, should not be the first on you try.

Re: ADHD Pill Faces High Hurdle in Europe as Stigma Persists

#4

I posted this in a HN thread about therapeutic uses of nicotine a week ago, but it's even more relevant here: > A friend of mine is a psychiatrist who specializes in treating ADHD. She told me about a conference she went to recently, where someone presented an interesting paper. > Apparently, there was an amazing study done relatively recently (last five years), in which they demonstrated that, in mice, exposure to n…

Of note: Adderall is by far not the only drug available for ADHD, and considering its addictive nature, should not be the first on you try.

What could be wrong with dosing children with amphetamines every day for years?

Re: ADHD Pill Faces High Hurdle in Europe as Stigma Persists

#5
> “There’s been a great deal of resistance to even believing there is a disease,” said Mary Baker, president of the European Brain Council, a Brussels-based non-profit representing doctors, patients and companies including Shire that work on neurology and psychiatry issues.

Here's a PDF of funding for the European Brain Council. (http://www.europeanbraincouncil.org/pdfs/Publications_/EBC%2...)

Re: ADHD Pill Faces High Hurdle in Europe as Stigma Persists

#6

I posted this in a HN thread about therapeutic uses of nicotine a week ago, but it's even more relevant here: > A friend of mine is a psychiatrist who specializes in treating ADHD. She told me about a conference she went to recently, where someone presented an interesting paper. > Apparently, there was an amazing study done relatively recently (last five years), in which they demonstrated that, in mice, exposure to n…

Of note: Adderall is by far not the only drug available for ADHD, and considering its addictive nature, should not be the first on you try.

What would you recommend?

Re: ADHD Pill Faces High Hurdle in Europe as Stigma Persists

#7

Earlier quoted context omitted.

Of note: Adderall is by far not the only drug available for ADHD, and considering its addictive nature, should not be the first on you try.

What could be wrong with dosing children with amphetamines every day for years?

What do you suspect?

Re: ADHD Pill Faces High Hurdle in Europe as Stigma Persists

#9
Some of the signs for ADHD from wikipedia:

"Become bored with a task after only a few minutes, unless doing something enjoyable"

"Have trouble completing or turning in homework assignments"

"Struggle to follow instructions"

"Be very impatient"

"Be constantly in motion"

"Thinks constantly being told what to do by others for 18 years kinda sucks"

http://en.wikipedia.org/wiki/Attention_deficit_hyperactivity...

Re: ADHD Pill Faces High Hurdle in Europe as Stigma Persists

#10
post #6

Earlier quoted context omitted.

Of note: Adderall is by far not the only drug available for ADHD, and considering its addictive nature, should not be the first on you try.

What would you recommend?

First off, I recommend you ask a licensed professional that type of question.

My experience being switched from Adderall XR to Vyvanse a few years ago when it first came to market in the U.S. has been positive. Vyvanse seems less addictive (missing a week or two between prescriptions is not a big deal) or prone to side effects like insomnia.

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