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Nicotine as a useful stimulant

gwern.net

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Re: Nicotine as a useful stimulant

#2
I can't imagine life without stimulants. I hope to move off into the woods one day and live a completely natural lifestyle for a while. Reset myself. No caffeine, no nicotine, no amphetamines. Just me, a dog, and a nice ranch property in the middle of nowhere.

Meanwhile, nicotine is a staple of my day-to-day. I quit smoking a long time ago, now I stick to Swedish snus and vaping. For a period I was chewing gum too. Definitely lots of ways to get it without smoking.

Re: Nicotine as a useful stimulant

#5
From anecdotal experience, nicotine has quite a similar effect to amphetamine (therapeutic dosing.. i.e. Adderall).

Nicotine, in low doses, by itself (i.e. outside of tobacco, which contains MAOIs, which potentiate nicotine's effects), is not terribly addictive. I'll occasionally supplement it for a few days at a time, then stop. I would caution anyone supplementing nicotine NEVER to smoke tobacco, at the same time.

Patches are the most healthy way to consume nicotine. Nicotine + gums = all kinds of bad stuff. Still, there's some slight carcinogenic risk with long-term use of the stuff, so it's not a miracle drug. :(

Re: Nicotine as a useful stimulant

#6
I'm very sad this article doesn't mention the most interesting quality of nicotine: depending on how it is administered, it will act either as a sedative, or a stimulant!

There's not (m)any other molecules out there that do this, so it's quite a novel research target!

Re: Nicotine as a useful stimulant

#7

I vaped for a while on the strength of this analysis, but eventually concluded that stimulants weren't worth the blood pressure increase. I still vape zero nicotine ejuice though. That stuff is delicious.

i'm vaping and lowering my doses of nicotine while i go. hopefully, i can get to zero nicotine.

Re: Nicotine as a useful stimulant

#8

I vaped for a while on the strength of this analysis, but eventually concluded that stimulants weren't worth the blood pressure increase. I still vape zero nicotine ejuice though. That stuff is delicious.

Your body will rapidly develop tolerance for the blood pressure increase caused by many stimulants (caffeine, nicotine). You will likely see no more effect after just a few days.

Re: Nicotine as a useful stimulant

#9
post #4

Once demonization has eradicated tobacco from the public's grasp, these benefits may be sold back in pill form for an even greater margin of profit. Yay Capitalism!

You should read the article. He prices out nicotene for you. It's... not going to make anyone wildly rich the way cigarettes did.

Re: Nicotine as a useful stimulant

#10
post #7

I vaped for a while on the strength of this analysis, but eventually concluded that stimulants weren't worth the blood pressure increase. I still vape zero nicotine ejuice though. That stuff is delicious.

i'm vaping and lowering my doses of nicotine while i go. hopefully, i can get to zero nicotine.

Doing the same here. It also helps that my non-nicotine juice tastes much better than the one with nicotine. Good luck!
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