1: I realize this is their first attempt at this, but if this phone doesn't support 2+ monitors, then this simply won't work as a desktop replacement. HDMI-output is nothing new. Who still uses a single monitor on their desktop?
2: I didn't find any mention of docks. I'd be interested to see if there would be any future plans to create different types of docks. I.e. tablet dock with extended battery life (like the Asus PadFone), desktop dock with 2+ 1080p+ monitor output. Preferably with the docks allowing USB connections, so that we are not stuck with buying new gear all around. Maybe even a laptop style dock?
3: Context awareness. Not sure if this is already addressed, but it'd be nice if when I docked it at work, I'd have the option of continuing where I left off yesterday. Achievable through profiles combined with some NFC cleverness? Personally, I can think of a few contexts I'd set up myself: desktop@work, desktop@home, laptop, tablet, HTPC, nightstand, car... and of course, phone.
4: Waterproof. If I'm going to walk around with my personal computer in my pocket, it'd be nice if a splash of water didn't kill it.