That being said, I found the article interesting, but, as a biochem major, fairly unsurprising. Fructose and glucose are fundamental elements of our body's metabolism, and metabolism is a fundamental element to life. It's what gives your cells energy to do every single thing they do. That sucrose, a compound made up of a single fructose molecule bonded to a glucose molecule, is not detrimental to your health given reasonable consumption reaches "duh" levels of obviousness. Same is true of high fructose corn syrup, which actually just contains 55% fructose and 42% glucose, a negligible difference. So it seems the only detriment to your health posed by HFCS over sucrose is the anxiety you'll get by worrying about it.
Like someone else said "TL;DR: stop eating so much, fatty." In more practical terms, eat reasonably and lift weights and you'll be fine.
Edit:
Here's some science for you:
Energy in = Energy out + Change in Body Stores (fat or muscle)
Where "energy" is measured in calories. Laws of thermodynamics ain't nothin' to f with! [1]
[1] http://www.bodyrecomposition.com/fat-loss/the-energy-balance...