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More Nootropics: Racetams and Glycinergics

examine.com

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Re: More Nootropics: Racetams and Glycinergics

#21

Post by simpsond »

tokenadult wrote: post #18

In every discussion I have seen of "smart drugs" (nootropics), what is conspicuously lacking is discussion of the actual smart deeds performed by the smart drug users. Self-reported n=1 anecdotes have not established a convincing case that any kind of nootropic actually does anyone any good in the real world. (Maybe I'll edit this comment some more below during its editing time window. Or perhaps this point is so evi…

We can't accurately meter our performance, intelligence, and behavior. We also can't control our environment (not realistically anyways). So, it's anecdotal. I'm excited for sensor networking to get in the body, so we can actually measure the effects of our consumption. Then again... that doesn't measure behavior, or intelligence. It's a hard problem.

Re: More Nootropics: Racetams and Glycinergics

#22

Post by enraged_camel »

simpsond wrote: post #21
tokenadult wrote: post #18

In every discussion I have seen of "smart drugs" (nootropics), what is conspicuously lacking is discussion of the actual smart deeds performed by the smart drug users. Self-reported n=1 anecdotes have not established a convincing case that any kind of nootropic actually does anyone any good in the real world. (Maybe I'll edit this comment some more below during its editing time window. Or perhaps this point is so evi…

We can't accurately meter our performance, intelligence, and behavior. We also can't control our environment (not realistically anyways). So, it's anecdotal. I'm excited for sensor networking to get in the body, so we can actually measure the effects of our consumption. Then again... that doesn't measure behavior, or intelligence. It's a hard problem.

What we need is double-blind studies with proper control groups and behavior or problem-solving tests.

Re: More Nootropics: Racetams and Glycinergics

#23

Post by droopyEyelids »

tokenadult wrote: post #18

In every discussion I have seen of "smart drugs" (nootropics), what is conspicuously lacking is discussion of the actual smart deeds performed by the smart drug users. Self-reported n=1 anecdotes have not established a convincing case that any kind of nootropic actually does anyone any good in the real world. (Maybe I'll edit this comment some more below during its editing time window. Or perhaps this point is so evi…

Thank You.

I look at this smart drug crap as a weird cultural thing to study.

If smart drugs made people have better performance, you'd notice your coworkers outperforming you while grimacing down their powdered piracetam. The army would be using them. Doctors would be making statements.

Re: More Nootropics: Racetams and Glycinergics

#24

Post by 1qaz2wsx3edc »

enraged_camel wrote: post #22
simpsond wrote: post #21

Earlier quoted context omitted.

We can't accurately meter our performance, intelligence, and behavior. We also can't control our environment (not realistically anyways). So, it's anecdotal. I'm excited for sensor networking to get in the body, so we can actually measure the effects of our consumption. Then again... that doesn't measure behavior, or intelligence. It's a hard problem.

What we need is double-blind studies with proper control groups and behavior or problem-solving tests.

Which is what examine.com attempts to expose/deliver. It's not perfect it.

Re: More Nootropics: Racetams and Glycinergics

#25

Post by drewblaisdell »

tokenadult wrote: post #18

In every discussion I have seen of "smart drugs" (nootropics), what is conspicuously lacking is discussion of the actual smart deeds performed by the smart drug users. Self-reported n=1 anecdotes have not established a convincing case that any kind of nootropic actually does anyone any good in the real world. (Maybe I'll edit this comment some more below during its editing time window. Or perhaps this point is so evi…

There are, however, studies that show that racetams are not harmful. If you don't believe they work, give them a try for yourself. They work for some and not for others.

Did you consult a double-blind study of caffeine before drinking your first cup of coffee? At what point does the plural anecdote at least refute the idea that racetams are just a placebo?

Re: More Nootropics: Racetams and Glycinergics

#27

Post by seletskiy »

najhr999 wrote: post #2

Anyone use nootropics and want to share their usage/experience?

I took glycine, semaks (Met-Glu-His-Phe-Pro-Gly-Pro), piracetam for about several months, and, finally phenylpiracetam (it's called phenotropil in Russia) some time ago.

I've notice entirely no effect from any of this drugs with except of phenylpiracetam.

While I've used phenylpiracetam, I've noticed some effects: 1) I've got more physical endurance (I'm engaging in sports a lot) just from one doze of it; 2) My overall alertness arises; 3) My visual perception became more clear and vivid; 4) I was able to maintain focus for extended periods of time; 5) It was easy to wakeup and harder to sleep down earlier (my brain was like "so much ideas, need to think it all").

When I stop taking phenylpiracetam all of these effects gone away.

Re: More Nootropics: Racetams and Glycinergics

#28

Post by aaxe »

samwilliams wrote: post #11

> The glycerinergics are those molecules that can bind to what is known as the 'glycine binding site' of a particular subset of stimulatory receptors (NMDA), and it seems that by stimulating this binding site the overall signalling is increased. 'Glycerinergics' has only one result on Google - this article. Even if we assume that they mean it in the same way as we talk about GABAergic or dopaminergic drugs the defini…

The article links to the actual listing pages, which go into full details.

Re: More Nootropics: Racetams and Glycinergics

#29

Post by najhr999 »

sycamore wrote: post #3
najhr999 wrote: post #2

Anyone use nootropics and want to share their usage/experience?

I take noopept 20mg daily sublingually or orally, and occasionally modafinil. Modafinil works really well for me (300/400mg keeping me awake and FOCUSED but not buzzing/twitchy) but worked poorly for my brother (no noticeable effect at similar dosage). Since taking noopept I have noticed more of a willingness and now desire to learn, something which was an issue in my past. It also seems to help me work for prolonged…

How do you obtain Modafinil?

Re: More Nootropics: Racetams and Glycinergics

#30

Post by aaxe »

samwilliams wrote: post #11

> The glycerinergics are those molecules that can bind to what is known as the 'glycine binding site' of a particular subset of stimulatory receptors (NMDA), and it seems that by stimulating this binding site the overall signalling is increased. 'Glycerinergics' has only one result on Google - this article. Even if we assume that they mean it in the same way as we talk about GABAergic or dopaminergic drugs the defini…

You do realize its talking about the neuron, not the synapse? They are quite different.
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