I think we've exhausted any vein of disagreement. That said, there's one thing I want to point out:
I think you're overestimating the extent to which there are any natural principles that'll set in and show their hand; they're out there, but most human behavior that actually bumps into them gets corrected pretty fast, all things considered (a few decades, usually, between discovery and adaptation).
For most of the debates of interest there aren't really principles you can fall back on, and even if you do there's a big "so what?", because principles do not in and of themselves supply a valuation.
Let's stick with secondhand smoke.
Let's assume it comes out that, eg, using much-more-definitive science than anything we currently have on the matter that there's a non-zero but seemingly negligible increase in risk of lung cancer from second-hand smoke (say: above some level of exposure your risk of lung cancer becomes 0.0002% instead of .0001%).
This seems compelling, but at the end of the day it doesn't really help you resolve the issue of "secondhand smoke regulation" (without the backing of some state to dictate the resolution).
It might be irrational, say, for the consensus opinion to be that secondhand smoke is worth banning even though other, unbanned activities have higher risks, but so what? The point of "owning" something is being able to do what you like with it without having to justify those actions to others; matters of fact can make certain conversations more likely to go one way instead of another but they ultimately are just dead facts on the table.
An extreme example is something like trying to build an apartment complex over an indian burial ground; it's a pure battle of aesthetics that can't be won by reason alone.
The "second-hand smoking" issue is only superficially different: it seems like there's more of a scientific aspect (does second-hand smoking actually cause harm?) but those facts only serve to inform the parties; without some agreement on underlying outlooks (how to interpret those facts) the facts don't do anything.
One of the commonest forms of self-delusion in internet political arguing is to (unconsciously) assume enough about "the other side's" core beliefs and assumptions that for them to disagree with the conclusions you've drawn would be irrational; this isn't usually an intentional mistake, it just arises from a failure to conceptualize other people's outlooks as differing from your own in any fundamental way.
What I see this century holding is (sadly) a huge flux in underlying outlooks; even when there are principles they depend on pragmatics to accomplish anything, and failing to deal with that flux will lead to sucking at pragmatics.
I'm out, it's been a pleasant sunday.