Anyone care to weigh in about using this vs., say, TastyPie?
We looked at and started playing with TastyPie over at Pathwright, but ultimately found that it was very difficult to customize to our needs (mostly with respect to custom API resources, custom filtering, and very fine-grained permissions based on a number of factors). The documentation isn't organized very well, and at the time (a few months ago), it appeared that development had stalled.
After getting pretty frustrated with TastyPie, we gave rest-framework a try as a last resort before we'd consider doing our own thing. So far, we have found rest-framework to be a whole lot more readable, much more actively maintained, much easier to get help for, and much easier to customize permissions and queryset filtering for.
To us, this ended up being a no-brainer. rest-framework has less magic, it is less complicated, it was easier for us to customize, and the organization of the documentation makes more sense.
But, as with most things, YMMV. We really like rest-framework, but don't take my word for it.