Quick Poll (programming preference)

PHP all the way, and maybe .NET for some apps

django, PostgreSQL

Python + Postgres, or ColdFusion + Postgres. Failing that, I'd choose PHP if there's a chance anyone besides me will ever touch the project, or Ruby if its gonna be me all the way. Just because good php coders are easier to come by than Ruby ones, and because you've added "Scaling" as an item. I'm saying Python and Ruby and not Django/Pylons/Rails because I won't pick a framework be default - only if it 100% fitted a particular project. Otherwise I'd rather code it myself from scratch. Harel

PHP 5 all the way + MySQL or Postgres.

I've been enjoying RoR + MySQL, but I haven't launched a project that has any widespread audience yet.