Haxe anyone ? full HTML5 api support , dead-code elimination, loads of libraries and frameworks , easy integration with third party libraries ,multi-target (C++,Flash,JS,...) and open source...
Not that the game has been called, Typescript and Dart themselves have been out for a while and don't really took large slices of the pie. The biggest "transpiled" Javascript language is still Coffeescript, and that's basically Ratfor for the web.
There's also Opa and Fantom, if we're going even more esoteric...