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Nanoparticles loaded with bee venom kill HIV

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Re: Nanoparticles loaded with bee venom kill HIV

#12
post #10

So this is not intended as a cure, and can not function that way. Rather it's for use as a protective to prevent someone getting infected. And it might have value as a treatment (but I'm guessing it will be too toxic inside blood).

Hood also sees potential for using nanoparticles with melittin as therapy for existing HIV infections, especially those that are drug-resistant. The nanoparticles could be injected intravenously and, in theory, would be able to clear HIV from the blood stream.

Re: Nanoparticles loaded with bee venom kill HIV

#14
post #12
post #10

So this is not intended as a cure, and can not function that way. Rather it's for use as a protective to prevent someone getting infected. And it might have value as a treatment (but I'm guessing it will be too toxic inside blood).

Hood also sees potential for using nanoparticles with melittin as therapy for existing HIV infections, especially those that are drug-resistant. The nanoparticles could be injected intravenously and, in theory, would be able to clear HIV from the blood stream.

But the reservoir for HIV infection, the thing that makes clearing HIV particles from the blood insufficient to cure it, is the CD4 T-cell. So just clearing the blood of HIV will not be curative.

Re: Nanoparticles loaded with bee venom kill HIV

#15
post #12
post #10

So this is not intended as a cure, and can not function that way. Rather it's for use as a protective to prevent someone getting infected. And it might have value as a treatment (but I'm guessing it will be too toxic inside blood).

Hood also sees potential for using nanoparticles with melittin as therapy for existing HIV infections, especially those that are drug-resistant. The nanoparticles could be injected intravenously and, in theory, would be able to clear HIV from the blood stream.

I have no idea what clearing HIV from the blood stream would achieve? I assume it is not a cure, but might help reduce risk of transmission or something?

Edit: Question answered whilst I wrote it! <3

Re: Nanoparticles loaded with bee venom kill HIV

#16
post #10

So this is not intended as a cure, and can not function that way. Rather it's for use as a protective to prevent someone getting infected. And it might have value as a treatment (but I'm guessing it will be too toxic inside blood).

It might be able to arrest an infection's internal spread to other tissues and cells, but the virus would still live in existing infected cells. They'd have to find the therapeutic levels necessary to "cleanse the blood", and do clinical trials to look for side-effects (since they'll've introduced a solution of foreign bodies into the bloodstream). It might be that the levels to cleanse the blood are too high in most cases to be economically or therapeutically viable; or maybe not.

In any case, the approach is pretty neat.

Re: Nanoparticles loaded with bee venom kill HIV

#18
post #12

Earlier quoted context omitted.

Hood also sees potential for using nanoparticles with melittin as therapy for existing HIV infections, especially those that are drug-resistant. The nanoparticles could be injected intravenously and, in theory, would be able to clear HIV from the blood stream.

But the reservoir for HIV infection, the thing that makes clearing HIV particles from the blood insufficient to cure it, is the CD4 T-cell. So just clearing the blood of HIV will not be curative.

I don't have much biology experience, but if you can keep the blood stream clear of HIV, wouldn't that prevent new T-cells from getting infected, allowing the count of healthy T-cells to start growing as the body makes new ones?

Re: Nanoparticles loaded with bee venom kill HIV

#19
post #12

Earlier quoted context omitted.

Hood also sees potential for using nanoparticles with melittin as therapy for existing HIV infections, especially those that are drug-resistant. The nanoparticles could be injected intravenously and, in theory, would be able to clear HIV from the blood stream.

But the reservoir for HIV infection, the thing that makes clearing HIV particles from the blood insufficient to cure it, is the CD4 T-cell. So just clearing the blood of HIV will not be curative.

I'm not a biologist either; but, a thought: if the body is protected from greater infection while still keeping its infection levels constant, could the body then actually create successful antibodies for the existing HIV in them, and become cured over time?

Re: Nanoparticles loaded with bee venom kill HIV

#20

the HIV-AIDS hypothesis is a hoax instigated by a cancer fraud. See Duesberg.com for details.

http://www.niaid.nih.gov/topics/HIVAIDS/Understanding/howHIV...

While there is no definitive study that shows a direct correlation, there is enough evidence to satisfy Koch's postulates for infectious cause (even if the ultimate cause of AIDS is not singular or an incidental byproduct of HIV). Show me a double blind study indicating that HIV is not a cause of AIDS and I'll show off the science.

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