Why Aaron died

As to your claim that "they do not work", the scientific evidence that they work may be questionable, but lack of scientific proof is not the same thing as scientific disproof. You have no proof that they do not work for many people, despite your claim, as the way the drugs are used in double-blind studies do not perfectly mirror their use in the actual world. E.g., combination with other drugs, such a benzos, and/or other antidpressants, and trials of a number of different drugs to find which one is best of that particular person's brain chemistry.

Furthermore, one doesn't need scientific evidence to know certain things. I don't need published double-blind scientific evidence to know that if I hit my toe with a hammer that it will hurt. I don't need scientific evidence to know that my wife loves me.

Another point of evidence: Paxil also cured my depression within a day or two, on a different occasion, but it also had many other effects on me that were highly undesirable. It removed all pleasurable sexual sensations. It made me hypomanic and not care about how I treated other people. I felt as if everyone else in the world was an asshole who didn't give a shit about me, and so I was free not to give a shit about them. I felt absolutely no affinity any more for the people that I loved. I only found them annoying. I.e., my normal personality was turned completely upside down.

I don't need scientific evidence to know that this is how Paxil effected me, any more than I need scientific evidence to tell me how alcohol or marijuana make me feel. These are not subtle things, and the effect of Paxil on me, and the affect of Remeron on me were anything but subtle. They were as psychoactive as any substance can be.

Now since my evidence is not scientific, I am not stating that you should be convinced. On the other hand, you have no grounds to assert that I was cured by the placebo effect. You don't know me and you don't have access to the personal experiential information I have. I, personally, have plenty of information to make an accurate and rational conclusion here. And I have.

With all respect, I most certainly can. I know myself well enough to know how I respond to drugs. I'm sorry if that is not the case for you. I also know that I don't suddenly pop from the depths of the worst despair imaginable to being completely normal in a day or two on a hope and a dream. If that were the case, many other things would have cured me. Such as the dozen or two medications I tried before Remeron, for instance.

> The only way this claim could become scientific would be with a double-blind scientific study. Such a study would compare the drug with ... a placebo

I specifically stated that my claim was not scientific. All knowledge does not come via science. As I already mentioned, I cannot prove scientifically that my wife loves me, and yet I know this to be true. You may have no good reason to believe me about that, but that has no bearing on what I know to be true.

> Yes, which means it's a good thing that I never said that anywhere. And why would I? The claim makes no sense -- no one is ever "cured" by the placebo effect.

The placebo affect is real, so it can certainly act as a cure for minor ailments of certain sorts. I have no desire to argue semantics with you. On the other hand, it was Remeron that cured me, and I'm as sure of that as I am that I am not conversing right now with an AI program, though I can't prove that scientifically, either.

As I also mentioned, you do have not have any particularly good reason to believe me, but for reasons I have stated, you also have no good reason not to believe me. If you were not an ideologue, you would remain agnostic.

> Wow. The drug companies must love clients like you.

Your assertion is that a drug company would love me because I am willing to testify to the fact that Paxil made me hypomanic and I would assert to anyone that it is a dangerous drug and I would advise them to stay away from it if my experience is at all representative? You have a strange notion of what drug companies might love.

I've been told by doctors that I had a phobia of antidepressants because I was so utterly resistant to trying anymore after my terrible experiences with them. You sound like them: The hypomania was all in my head. The sexual dysfunction from Prozac was all in my head! Welcome to the club of quack shrinks!

> You are ignoring the readily available scientific findings, so no, your conclusion is neither accurate nor rational.

I am ignoring nothing. If you actually read what I wrote, you would know that.

As to your claims that neuroscience research will likely be hugely beneficial to our understanding. Well, of course. That verges on tautology.

> With all respect, I most certainly can.

I recommend a refresher course in science.

"Ohhh your wife was shouting at you? I hear ya, buddy. I'll drop most of the charges and you won't have to go to jail for murder..."

I mean, come on. We can't take people's personal circumstances that are unrelated to the crime into account. No matter if you are rich or poor, married or single, working or unemployed, kids or no kids, you should get equal treatment under the law. I can't believe people are arguing that "possibly suicidal" people should have charges reduced. If that was true, everyone charged with a crime would claim to be suicidal...