I am freaking out. This is a huge moment. I don't want to drag the discourse away from this achievement, but I hate how this is announced with blatant corporate advertising (our internal model, here are the benchmarks, gpt astra TM yours now for the low low price of £200pcm). I just didn't think Navier-Stokes falling would be sponsored by McDonald's. Still. I am crying right now. Navier-Stokes is solved.
AlphaGenome Atlas: a high-resolution map of human DNA
71–80 of 133 posts
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#72Earlier quoted context omitted.
> Market reward is the best proxy for good we have. Only if the goal is profit. All else be damned. > What's your alternative? Executive fiat? Mob rule? It is always bewildering to me that people see the world being raped by corporations and their negative externality, and they think that this is the pinnacle that humanity can achieve. Nothing else can be better, if all your options are "mob rule" or "executive fiat"…
[flagged]
Proceeds to write a rant that would make r/teenagers blush, based on a misunderstanding of the word misanthrope.
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#73I am freaking out. This is a huge moment. I don't want to drag the discourse away from this achievement, but I hate how this is announced with blatant corporate advertising (our internal model, here are the benchmarks, gpt astra TM yours now for the low low price of £200pcm). I just didn't think Navier-Stokes falling would be sponsored by McDonald's. Still. I am crying right now. Navier-Stokes is solved.
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#74I am freaking out. This is a huge moment. I don't want to drag the discourse away from this achievement, but I hate how this is announced with blatant corporate advertising (our internal model, here are the benchmarks, gpt astra TM yours now for the low low price of £200pcm). I just didn't think Navier-Stokes falling would be sponsored by McDonald's. Still. I am crying right now. Navier-Stokes is solved.
Wait, is NS solved? I thought I was just a singularity thing?
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#75Earlier quoted context omitted.
What are you even talking about? What do you mean catch a break? They’ve made massive contributions over the last decade.
I think orliesaurus meant the PR team is unable to rest because the rest of Deepmind is so prolific and keep coming out with new things for them to announce
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#76Earlier quoted context omitted.
I think orliesaurus meant the PR team is unable to rest because the rest of Deepmind is so prolific and keep coming out with new things for them to announce
I don’t think so. The tone of the comment seems derogatory.
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#77https://www.science.org/content/blog-post/mutate-em-all-and-...
which comments the results of this study:
https://www.biorxiv.org/content/10.64898/2026.07.25.740675v1
That study has done in reality what the AlphaGenome Atlas does in fiction, but instead for a human they have done it for one of the simplest viruses.
So they have fuzzed the virus by mutating one by one each position of its DNA.
And various dedicated AI models all made poor predictions of the results of that experiment, which casts doubts about the value of the AlphaGenome predictive map.
A virus is much simpler than a human, but even for that simple virus the effects of most of the mutations could not be predicted. A half of the mutations had harmful effects, and for a half of those it is unknown for now why they were harmful.
For a human the uncertainty about the effects of a mutation will be far greater than for one of the simplest viruses.
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#78Earlier quoted context omitted.
Not really, no.
Why not? There is no logical reason as to why this would not work, IF it works in the first place, which I don't know. In theory the problem space here is finite, so there is of course a way to predict everything. Whether this is the case right now - who knows; I probably don't think it is currently ready. But eventually it will be. And it should not be in the hands of private companies.
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#79Re: AlphaGenome Atlas: a high-resolution map of human DNA
#80Earlier quoted context omitted.
Market reward is the best proxy for good we have. What's your alternative? Executive fiat? Mob rule? Deepmind is objectively good. These endeavors would always cost money. Better private capital than state, no one has to give Google anything. The state is not so generous.
> Market reward is the best proxy for good we have. Only if the goal is profit. All else be damned. > What's your alternative? Executive fiat? Mob rule? It is always bewildering to me that people see the world being raped by corporations and their negative externality, and they think that this is the pinnacle that humanity can achieve. Nothing else can be better, if all your options are "mob rule" or "executive fiat"…
> I fancy myself a misanthrope, but damn, next to people in this forum I am probably the last humanist walking through the ruins of civilization.
A humanist who uses a term of sexual violence so cavalierly?
If you are in the United States and you want a good civic lesson in state power, you should go to your nearest metropolitan criminal court. Maybe you will have a more accurate view of what government means then. At the very least, you will likely learn to banish such a casual invocation of that word from your lexicon.
> Nothing else can be better, if all your options are "mob rule" or "executive fiat".
What we have now is the middle ground between king and mob. It took centuries and much carnage to achieve. Does the famous Churchill quote really need to keep being repeated? Do you have an alternative proposal? Or maybe you have a sensible proposal that falls within the established democratic bounds? Or perhaps instead by "would be a much nicer place if they ceased to exist" we should simply infer a generalized whining rather than any specific policy prescription?
What's your actual idea, do you have one?
Maybe if you endeavored to communicate without self-satisfied hyperbole you would find we actually have reason to agree with each other.