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AlphaGenome Atlas: a high-resolution map of human DNA

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31–40 of 131 posts

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#31
post #10

I really love Deep Mind, its genuinely focused on using AI to make the world a better place.

Be careful when loving shareholder-driven endeavors; they're a single executive decision away from breaking your heart.

Be careful when loving government/philanthropy/ngo-driven endeavors; they're a single executive decision away from breaking your heart.

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#32

the Google DeepMind PR team can't catch a break, shame it makes no sense to me - if someone's in the field maybe they could explain to the rest of us if this is a big deal, just a PR move, or nah?

What are you even talking about? What do you mean catch a break? They’ve made massive contributions over the last decade.

I think orliesaurus meant the PR team is unable to rest because the rest of Deepmind is so prolific and keep coming out with new things for them to announce

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#33
post #20

Earlier quoted context omitted.

PunchTornado was first, fr2029 was second

i made no such comment. reported for harassment.

so you just happen to be posting in a thread where some random user said you made a comment but you made no comments whatsoever

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#37
post #20

Earlier quoted context omitted.

PunchTornado was first, fr2029 was second

i made no such comment. reported for harassment.

You deleted the verbatim comment after it was pointed out. One was in thread and one was a stand alone comment. I was curious which was the throwaway so clicked into both profiles

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#38
post #31

Earlier quoted context omitted.

Be careful when loving shareholder-driven endeavors; they're a single executive decision away from breaking your heart.

Be careful when loving government/philanthropy/ngo-driven endeavors; they're a single executive decision away from breaking your heart.

Marriages too

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#39
post #21

Earlier quoted context omitted.

Be careful when loving shareholder-driven endeavors; they're a single executive decision away from breaking your heart.

It's "shareholder-linked" (probably not "driven"), but yes, upvoted. Nonetheless, even when with grave faults in the path, Google has managed to give us marvellous, paramount free resources (Google Street, Google Museum...), and would have given more (Google Books - if the negotiation had succeeded). I am grateful.

Google Streetview/maps isn't even the best mapping/'streetview' tool at this point. Filled with ads and bugs, some major bugs have been there for 10+ years.

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#40
I saw a really interesting talk by Katie Pollard at ISMB this year about the limitations of variant prediction.

The gist was, can existing variation provide enough context to infer impact of variation? The answer seemed to be no.

Kind of like how frontier LLMs need to ingest larger and large amounts of text to advance. We are going to need to leverage comparative data from other species, and likely tremendous amounts of laboratory mutagenesis experiments to actually make headway on variant prediction. Nature, as it stands, just doesn't have enough human variation.

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