To make the most facile counterpoint - the reason the Skyrim blacksmith doesn't care if the main character slays dragons is because they weren't programmed to. There aren't consequences either way. To the extent that this post is meant to be inspiring, it only works if you're an NPC in a static world that has no real consequences - where you actually can live your life in a static loop because nothing will change. Wh…
I think when people use NPC as an insult (it is a dumb insult in my opinion), they are looking at it from the point of view of a player, someone outside the game who understands that the NPC is scripted (this is a silly and egotistical way of looking at the world). This post is looking from it from the point of view of the NPC instead, as if that was a living entity one could be.
Your life isn't scripted. If have the option to not ignore the dragon. You can work with your town to setup a watch and places to flee to when the dragon is coming (even if only 50% make it that is an improvement). You can as a town fund adventures to kill the dragon. You can move to a town where there are no dragons. There are probably other options that I haven't thought of.
You should not ignore politics. You need to understand the trade offs. You should plan for what is happening. Russia is at war with Ukraine - things like that can happen to you as well. You should understand enough to have an informed decision on how much to prepare... Maybe you need to build a bomb shelter, maybe not, but you should know in time to build one.