Ask HN: Who is hiring? (September 2026)

Newtwen is building a cloud platform that brings complex physics and data-driven intelligence directly onto microcontrollers, generating ultra-fast runtime firmware that executes in just a few microseconds.

We're looking for a Senior Backend & Cloud Platform Engineer to help architect and build our first production-grade cloud backend from the ground up. You'll own backend services and computational pipelines spanning 3D geometry processing, mesh generation, model order reduction, calibration and neural network training.

A core part of the platform is dedicated to data-driven modeling, with a specialized neural-model library designed to make physical models adaptive in real time.

You might be a good fit if you have: strong production backend/cloud experience, Python (FastAPI or similar), relational databases, Docker, cloud infrastructure (GCP preferred), CI/CD and IaC — and enjoy making architecture decisions rather than just implementing tickets.

Location: REMOTE (EU), with the option to work hybrid in Italy Compensation: €70k–€90k+, depending on experience

Apply: career@newtwen.com — mention Hacker News and include your LinkedIn/CV and, if available, GitHub or project links.

Paramark helps Marketing teams optimize spend across all of their channels and programs. There are proven scientific ways to do this, but they are poorly understood and practiced by only a tiny fraction of teams. Our product ingests data from all of our customers' marketing channels and uses it to train open-source ML models for both measurement and experimentation. This makes it possible for any marketer to use these methods.

In this domain, it's hard to figure out what to build, and it's even harder to be both accurate and simple. You'll be joining a small team -- we have four product engineers. That means owning systems end to end and having real influence over what gets built. Your typical project will start with a high level goal, and you will figure out the rest.

Founded 2023, 15 people, $8M from Greylock and others, cash-flow positive. Reasonable working hours: when the Mercury News covered the return of 996 culture, we were the counterexample. "We don't think early stage startup life requires 18-hour days, or even 12-hour days." https://www.mercurynews.com/2025/08/25/silicon-valley-startu.... 4 weeks PTO plus federal holidays, medical/dental/vision (100% of employee premiums, 50% for family).

Looking for 8+ years, full-stack. Some exposure to statistics, experimentation, or A/B testing helps.

Stack: TypeScript, React, Python, Postgres. Google Cloud, Kubernetes, FastAPI, taskiq.

Process: intro call; technical phone screen; one-day onsite in SF (travel covered for remote candidates)

In-person: https://paramark.com/careers/software-engineer-l4

Remote: https://paramark.com/careers/software-engineer-l4-remote

I'm the CTO and I read every application myself. Happy to answer questions in this thread.

Biobase has grand ambitions. We broker biospecimens, whole slide images, and the clinical metadata attached to them, on a supply-chain backbone that we're steadily automating. We’re building healthcare-data-focused agents on top of the datasets that we’re assembling, too.

We'd rather build the thing that removes the work than throw people at it. Two roles, one team, both reporting to the CPO:

Senior Technical Product Engineer ($150–230k + meaningful equity). The product team's technical interface. Architecture decisions and code review on the platform (Python/FastAPI, TypeScript/React, Postgres, Azure); the data pipeline and informatics that take specimen, slide, and clinical data in from suppliers and labs; and product ownership of the internal platform that builds our agents (permissions, evals, cost control, guardrails for sensitive data). You've been the reviewer of record somewhere, you've operated what you shipped, and you think in business problems before tickets.

Technical Product Engineer, early career ($90–170k + equity). Same territory at an earlier stage: the platform, the data pipeline and informatics, and the agents we run against our own operations — with a senior product engineer and our lead engineer reviewing your work and pairing when it helps. Open on background – self-taught, bootcamp, degree, research lab, a career you're leaving – selective on the bar. You've built something and someone else used it.

We build with Claude Code every day and expect you to become both fluent with it and skeptical of it. No ticket queue, no spec handed to you. Comp is salary + equity combos you choose between.

Full postings: https://biobase.ai/careers

To apply: email jobs@biobase.ai with something you built that eliminated manual work and what happened after it shipped. Links over resumes, no cover letter.