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'Mad honey' that can stop your heart is being sold online

phys.org

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Re: 'Mad honey' that can stop your heart is being sold online

#51

Post by ux266478 »

culi wrote: post #4
daedrdev wrote: post #3

I imagine the native also built up tolerance over generations, not just knowledge as the article contends . Dying from a specific action is quite the evolutionary motivator

As with many psychoactive plants and foods, the adaptation here isn't so much a genetic/physiological tolerance as it is an often in-depth body of knowledge/practices for how to utilize the drug/medicine safely. Look at the notorious Datura for example which can cause you to go into a delirious state for over 2 days. The amount of preparation, processing, and knowledge that goes into administering it safely is lost o…

Most kids that are ingesting the devil's trumpet are doing so explicitly because they're chasing after the anticholinergic toxidrome and the badge of honor. "Safe" doses of nightshades like datura and belladonna dilate your pupils and make you sleepy. That's not what they're interested in the plant for.

Re: 'Mad honey' that can stop your heart is being sold online

#52

Post by trelane »

nozzlegear wrote: post #9
meindnoch wrote: post #5

A lot of things sold online can stop your heart.

A reasonable person wouldn't expect honey to stop their heart though.

I suspect if you're buying mad honey that's collected wild on cliff faces and then imported from Nepal, it is likely pretty clear to whoever got it that it is special.

Maybe kid could accidentally get a hold of it, or other adults that didn't buy it. However, from the article (as far as I could get before the ads locked me out) there is a type that tends to have this happen to them (middle aged men IIRC). So it seems to be intentional.

Re: 'Mad honey' that can stop your heart is being sold online

#53

Post by kayodelycaon »

Bang2Bay wrote: post #7
meindnoch wrote: post #5

A lot of things sold online can stop your heart.

Name a few. I want to be an informed person.

Tobacco can make you really sick if ingested.

Anything distilled may contain methanol.

Mushrooms can be a different type than what’s on the label.

Fermented products may contain poisons from dangerous bacteria. If you’ve heard about entire churches full of people dying in South America from bad food, it most likely fermented corn.

Expired food products may be contaminated with bacteria. (Unless they canned, jarred, or too dry Etc.)

Fresh apples may contain enough pesticide to make you sick. Wipe them off with a paper towel before use if you’re not peeling them.

Re: 'Mad honey' that can stop your heart is being sold online

#54

Post by riazrizvi »

blacksmith_tb wrote: post #46
riazrizvi wrote: post #41

Earlier quoted context omitted.

Florida's manchineel tree (with the tiny apples) is the OG wood you don't burn because it blinds you.

Or oleander [1], which people occasionally poison themselves with by burning its wood. 1: https://www.sciencedirect.com/topics/immunology-and-microbio...

Fascinating. So it seems to have been used for parasitic and fungal skin treatments, angina, and to induce miscarriage. With no doubt a very narrow band of error.

Re: 'Mad honey' that can stop your heart is being sold online

#55

Post by pnw »

SoftTalker wrote: post #30
Dylan16807 wrote: post #26

> The problem is that the gap between a medicinal dose and a toxic dose is very small What's this claim based on? I don't think it's the rat study linked nearby. I looked through it and they didn't really compare doses. If it's a linear effect on dropping blood pressure, that seems like an overblown way to talk about it. If it's something else, I'd love to hear more.

I also wondered why, if it has this effect, it has not been purified to a standard concentration (or synthesized) and used to treat high blood pressure. Possibly because accidental overdose can be fatal?

Grayanotoxin is a neurotoxin with a lot of unpleasant side effects. It would make a terrible drug for high blood pressure.

Re: 'Mad honey' that can stop your heart is being sold online

#56

Post by maxerickson »

Dylan16807 wrote: post #26

> The problem is that the gap between a medicinal dose and a toxic dose is very small What's this claim based on? I don't think it's the rat study linked nearby. I looked through it and they didn't really compare doses. If it's a linear effect on dropping blood pressure, that seems like an overblown way to talk about it. If it's something else, I'd love to hear more.

If you maintain the pairing with the statement about the concentration in the honey varying, it's somewhat harder to argue that it is overblown.

The concentration varies considerably due to bees harvesting pollen from different flowers and from some batches of honey being mixed and some not.

Re: 'Mad honey' that can stop your heart is being sold online

#57

Post by skinfaxi »

Loughla wrote: post #23
culi wrote: post #4

Earlier quoted context omitted.

As with many psychoactive plants and foods, the adaptation here isn't so much a genetic/physiological tolerance as it is an often in-depth body of knowledge/practices for how to utilize the drug/medicine safely. Look at the notorious Datura for example which can cause you to go into a delirious state for over 2 days. The amount of preparation, processing, and knowledge that goes into administering it safely is lost o…

Datura is fucking dangerous. Deliriants are no joke in general. That one in particular is really dangerous because it grows absolutely anywhere and is very easy to identify. Source; chemistry was my favorite class in high school and college because it helped me understand how to extract what I wanted from plants like jimsonweed and Mimosa trees. Also no one should do that.

As someone who as extracted dmt from mimosa hostilis, more people should do it than buy god knows what RCs on the darkweb.

Re: 'Mad honey' that can stop your heart is being sold online

#58

Post by dolebirchwood »

pigbearpig wrote: post #32
phoronixrly wrote: post #25

Earlier quoted context omitted.

[flagged]

What makes you say it's LLM? > Every article you read here is written by university scholars and researchers with deep expertise in their subjects, sharing their knowledge in their own words. We don’t oversimplify complicated issues, but we do explain and clarify. We believe bringing the voices of experts into the public discourse is good for democracy.

> What makes you say it's LLM?

Probably the usual "big words hard" mindset of people who aren't used to reading well-written prose.

Re: 'Mad honey' that can stop your heart is being sold online

#59

Post by Dylan16807 »

maxerickson wrote: post #56
Dylan16807 wrote: post #26

> The problem is that the gap between a medicinal dose and a toxic dose is very small What's this claim based on? I don't think it's the rat study linked nearby. I looked through it and they didn't really compare doses. If it's a linear effect on dropping blood pressure, that seems like an overblown way to talk about it. If it's something else, I'd love to hear more.

If you maintain the pairing with the statement about the concentration in the honey varying, it's somewhat harder to argue that it is overblown. The concentration varies considerably due to bees harvesting pollen from different flowers and from some batches of honey being mixed and some not.

> If you maintain the pairing with the statement about the concentration in the honey varying, it's somewhat harder to argue that it is overblown.

Those are two separate worries connected by an "and". I'm not arguing worry #2 is overblown.

And it sounds like the problem of variance is that it isn't small. If one batch can be 5x as strong as another (made up number), then even a pretty good medicinal response curve leaves you vulnerable to that much variance.

Re: 'Mad honey' that can stop your heart is being sold online

#60

Post by GaProgMan »

rubyfan wrote: post #34
robotnikman wrote: post #27

>Eat a teaspoonful, and you might feel pleasantly warm and slightly lightheaded. Eat more than a few tablespoons, and your heart rate can drop to life-threatening levels. Reminds me of the Futurama episode with the space bee honey. Wonder if the writers got the inspiration from this.

You’ve got to wake up.

I have a genuine fear that someone will stop me in the street one day, grab me by the shoulders and say

> You have to wake up. Please wake up. We're all here at your bedside waiting for you to wake up. Just wake up. We love you. Please.

And I'm convinced it's because of that episode.

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