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FDA authorizes first wearable device that monitors ketone and blood sugar levels

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Re: FDA authorizes first wearable device that monitors ketone and blood sugar levels

#131

Earlier quoted context omitted.

Cardiac surgery, burn units, ICU, neuro come to mind. All have been studied to show mortality and complications improvements with AGC, but unfortunately the commercial technology has not materialized yet.

Why is a hospital setting so different that AGC can not be used? Or is the temporary use of such not yet approved?

Drug interference (with the sensor chemistry) and perfusion (which the sensor needs to function) are two major problems that a hospital presents that are not present in ambulatory (outside the hospital) use. Also the FDA has not approved any systems yet; the software is actually quite difficult to get right.

Re: FDA authorizes first wearable device that monitors ketone and blood sugar levels

#133
post #87
post #48

Earlier quoted context omitted.

> Automated glucose control will be the next frontier in so many areas of healthcare. What areas do you have in mind outside of diabetes management?

Blood glucose levels affect lots of health functions. Diabetes represents an extreme end of the spectrum where the body's ability to regulate these fluctuations fails, but just because your body can get your levels in control eventually doesn't mean you won't suffer from the negative effects of it needing to do so. Maintaining consistent glucose levels improves mental health, weight management, sleep quality, muscle…

Do you think CGM + alerting is a good solution for this compared with just, like, low-dose GLP-1s?

Re: FDA authorizes first wearable device that monitors ketone and blood sugar levels

#134
post #113

A friend died of diabetic ketoacidosis. He loved technology and seeing people succeed. Thinking of him with this news. Miss you Dan. Grateful we're moving forward on so many fronts in the world.

He was my roommate in 2001 in San Jose. We came up with the idea of having a place where nerds could come together to hang out and learn from each other and we decided to call the concept "Hacker Dojo". I had a sign laser engraved in 2002 at a state fair to memorialize the idea but we didn't actually get to open a Hacker Dojo until 2009. There's a conference room in it called Kaminsky. Dan was not a very good roommat…

Dan was a spectacular brain, and made contributions that still echo today.

He is one of two friends to have passed from DKA. Miss you, Zach. RIP.

Miss pwning with you.

Re: FDA authorizes first wearable device that monitors ketone and blood sugar levels

#135

As someone who has to deal with type 1 diabetes every day, this is marketing nonsense. No one needs ketones in the sensor - we need high-quality sensors, and Abbott's are only mediocre at best. They are not as bad as Dexcom, which is appalling, but they are still far from the superior quality of Medtronic/MiniMed which measure glucose exceptionally well. Ketones are rare. They can kill you, but before that happens, y…

What's so bad about Dexcom and Freestyle compared to Medtronic CGMs?

Re: FDA authorizes first wearable device that monitors ketone and blood sugar levels

#136
post #87

Earlier quoted context omitted.

Blood glucose levels affect lots of health functions. Diabetes represents an extreme end of the spectrum where the body's ability to regulate these fluctuations fails, but just because your body can get your levels in control eventually doesn't mean you won't suffer from the negative effects of it needing to do so. Maintaining consistent glucose levels improves mental health, weight management, sleep quality, muscle…

sample of 1, but yeah changing my diet (very low sugar, more veggies) did alter my health visibly and rapidly. to the point that if I eat something too sweet too fast i have a very mild headache soon after, my system readjusted to not seek levels i grew up with

What happens is you lose carb tolerance if you don't take them regularly.

I had really high carb tolerance but doing keto for many years has plummeted it and I'm very sensitive now (can still train it). Another example doing keto for many years you also have lower alcohol tolerance.

Re: FDA authorizes first wearable device that monitors ketone and blood sugar levels

#139
post #91

Earlier quoted context omitted.

That's what I thought too, until I got my last bloodwork results and started wearing one of the OTC continuous glucose monitors. That device helped a lot to switch diet habits.

Can you be specific about what your bloodwork results showed and what special insights your CGM gave you and what behavioural changes it led to? My anecdotal experience from doctor colleagues giving CGM to patients is that it does 3/5ths of fuck all to everyone except those with actual insulin dependent diabetes (T1 or T2) because when you get down to it the insights aren’t that great and most people actually aren’t…

For sure it's going to depend on the person, but I bet a lot of the hacker news crowd here appreciates observability and metrics.

In software we're wiring up stuff with prometheus and making grafana dashboards and changing code and configuration based on what we see happening. CGMs in a way give you insight into one aspect of your body and diet.

I've been trying Lingo, and it's been super-interesting to see in almost realtime how your body reacts to different foods. Sure you read all the time about "watch your carbs..." or "don't eat so much sugar", but it's hard to know how seriously to take that advice.

It's a whole different thing though when you eat one thing for a snack and see a big spike in a graph on your phone, and eat a different thing the next day and see hardly any change at all. It makes it much easier to rationalize your food choices.

Re: FDA authorizes first wearable device that monitors ketone and blood sugar levels

#140
post #87
post #48

Earlier quoted context omitted.

> Automated glucose control will be the next frontier in so many areas of healthcare. What areas do you have in mind outside of diabetes management?

Blood glucose levels affect lots of health functions. Diabetes represents an extreme end of the spectrum where the body's ability to regulate these fluctuations fails, but just because your body can get your levels in control eventually doesn't mean you won't suffer from the negative effects of it needing to do so. Maintaining consistent glucose levels improves mental health, weight management, sleep quality, muscle…

I am confident that blood glucose has a lot to do with mood regulation as well.

Having been diagnosed with bipolar since 1997, when I began mainlining insulin last year I immediately took notice of how calm and docile I became. I have anger issues and taking insulin turned me into a lamb. I also immediately began sleeping peacefully and restfully, which had been elusive for a decade.

I currently take a calcium channel blocker for hypertension, and Metformin for the glucose, and I monitor with Stelo. But I would give anything for that calming effect of fast-acting insulin.

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