Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

Post by grokcodec » Wed, Aug 19, 2026, 3:59 PM UTC

rob74 wrote: post #77

grokcodec wrote: post #64

In other news, your barber thinks you need a haircut. Until there is a proven net overall health benefit to this therapy, I wouldn't waste much ink on it. Also, can someone please tell me how one controls the dose for an mRNA therapy ?

If you actually had melanoma (a very aggressive type of skin cancer) you would be glad for one more chance of maybe still being alive a few years from now.

Post by dosisking » Wed, Aug 19, 2026, 4:02 PM UTC

estearum wrote: post #66

Arkhaine_kupo wrote: post #41

Earlier quoted context omitted.

> People were assured that COVID vaccine mRNA would disappear within days and the spike protein would short-lived which is still the case, even in the Yale study. > That is a massive gap between what the public was told and what later evidence found. there is an even larger gap between basic epidemiology and what the public understands. Hard science is difficult to communicate on a good day, on a global pandemic with…

+1 the public health apparatuses' actual statements were impressively correct even if you don't account for the underlying uncertainty at the time. Where public health officials "failed" was not having a megaphone loud enough to drown out the game of telephone that most people (as these comment threads consistently show) were actually hearing information through. Simplest example: People will say that public health o…

Post by estearum » Wed, Aug 19, 2026, 4:03 PM UTC

ifyoubuildit wrote: post #67

cassidius wrote: post #39

Earlier quoted context omitted.

Except that your children are still vectors for getting others sick. Vaccines are there not just for you but your community.

Vaccines that have a large impact on transmission and infection are there not just for you but for your community. The covid shots were good against hospitalization and death in older folks, but they were not great at preventing infection or transmission (despite what you may have gleaned from the speakers blaring ads in every public setting for all that time). You can fall back to the "flooding the hospitals" argume…

Post by estearum » Wed, Aug 19, 2026, 4:04 PM UTC

dosisking wrote: post #83

estearum wrote: post #66

Earlier quoted context omitted.

+1 the public health apparatuses' actual statements were impressively correct even if you don't account for the underlying uncertainty at the time. Where public health officials "failed" was not having a megaphone loud enough to drown out the game of telephone that most people (as these comment threads consistently show) were actually hearing information through. Simplest example: People will say that public health o…

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Post by ryan_n » Wed, Aug 19, 2026, 4:05 PM UTC

dosisking wrote: post #76

ianlevesque wrote: post #31

Earlier quoted context omitted.

Saving a couple million people in the pandemic wasn’t validation enough?

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