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Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

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Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#61
post #14

Earlier quoted context omitted.

What are the reasons for the hate of the COVID vaccine?

There is a legitimate discussion of what can be mandated you do to your body. However, that discussion was largely side-tracked by the massive amount of disinformation (eg, "Plandemic") that circulated online. There are people who to this day swear that COVID-19 was just like the flu and simultaneously claim that the vaccine spike proteins have killed around 20M people. Not just crackpots, but people with reach, like…

> There is a legitimate discussion of what can be mandated you do to your body.

There is a legitimate discussion (dating back at least to Typhoid Mary (1) ) on excluding people from public spaces when they refuse to take basic public health measures. Taking a vaccine for a spreading deadly pandemic is one of those measures.

Doing something so violently anti-social is not simply a "bodily autonomy" issue, and framing it only as such is deeply misguided in a way that seems particular to some USA norms.

1) https://en.wikipedia.org/wiki/Mary_Mallon

> In 1907, she was forcibly quarantined at the Riverside Hospital

Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#62

Earlier quoted context omitted.

Probably one of the most polarizing issues of the last 5 years.

I don't recall it being as polarizing outside of the US, where there was a larger group of anti-vaxxers to begin with. But that might be my "outside US" bubble.

Oh it was, actually still is - our right wing party is still talking about this stuff regularly...

Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#63
post #14

Earlier quoted context omitted.

What are the reasons for the hate of the COVID vaccine?

Probably one of the most polarizing issues of the last 5 years.

You're not wrong, at least in the USA - but it really shouldn't be. The polarisation was ginned up for various bad reasons, including political gain. It's deadly culture war nonsense.

Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#66

Earlier quoted context omitted.

People were assured that COVID vaccine mRNA would disappear within days and the spike protein would short-lived. Yet Yale-led researchers later detected circulating S1 and full-length spike as late as 709 days after vaccination. They also left the public in the dark about the risk of vaccine-associated myocarditis, especially in young males, many of whom experienced permanent heart tissue damage. That is a massive ga…

> People were assured that COVID vaccine mRNA would disappear within days and the spike protein would short-lived which is still the case, even in the Yale study. > That is a massive gap between what the public was told and what later evidence found. there is an even larger gap between basic epidemiology and what the public understands. Hard science is difficult to communicate on a good day, on a global pandemic with…

+1 the public health apparatuses' actual statements were impressively correct even if you don't account for the underlying uncertainty at the time.

Where public health officials "failed" was not having a megaphone loud enough to drown out the game of telephone that most people (as these comment threads consistently show) were actually hearing information through.

Simplest example: People will say that public health officials told them "masks don't work." But no! Only one person did, and that was USSG Jerome Adams (who wasn't credible nor a major player to begin with). What public health officials said was "we do not know if masks work," which is a more nuanced but completely accurate statement.

Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#67
post #27

Earlier quoted context omitted.

[flagged]

Except that your children are still vectors for getting others sick. Vaccines are there not just for you but your community.

Vaccines that have a large impact on transmission and infection are there not just for you but for your community.

The covid shots were good against hospitalization and death in older folks, but they were not great at preventing infection or transmission (despite what you may have gleaned from the speakers blaring ads in every public setting for all that time).

You can fall back to the "flooding the hospitals" argument, that works a little better here.

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