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Where Human Sleep Went Wrong

nautil.us

41–50 of 139 posts

Re: Where Human Sleep Went Wrong

#41

I think people in HN (and in general) have to remember the central axes of evolution before digesting this kind of article. I've already seen comments like it's "odd that no species has ended up evolving a continuous maintenance system" and "sleep has a higher opportunity cost in humans" in this comments section. This is a common, but poor framing of evolution. Remember: the only real rule with evolution is "did this…

To be precise inclusive genetic fitness not idealized bayesian optimality.

Re: Where Human Sleep Went Wrong

#43

>“No way. They’re partying all night.” But they can, because there’s no top-down pressure to go into the office at 8 a.m. They’re free to catch supplemental sleep as needed throughout the 24-hour period. This feels like the key point to me. These societies follow their body and go to sleep when they are tried, while us in the west have to sleep at a specific time to fit our schedules.

A single block of sleep is a relatively new behaviour, I suspect partially driven by the availability of cheap sources of light and heat. https://www.bbc.com/future/article/20220107-the-lost-medieva...

That theory is on rather shaky grounds: https://pmc.ncbi.nlm.nih.gov/articles/PMC10404514/

Re: Where Human Sleep Went Wrong

#44
post #40
post #38

Earlier quoted context omitted.

I'm a biologist so forgive me the poor wording, but there are "infinitely high" peaks/walls in the evolutionary landscape, as in: "the human urinary system has some evolutionary constraints and anatomical features that are not optimally designed from an engineering perspective, but they are generally functional and reflect our evolutionary history rather than deliberate design." So in that sense, a global maxima (min…

That is the difference between global and local optima. We're not at a local optimum though, our bodies can probably evolve to produce half the urine or something without changing the route, but there is no evolutionary pressure to do so.

Yes, but we cannot evolve to have our urinary tracts take a more efficient route (or at least the probability is exceedingly low), even though there would be pressure to do so. (Maybe I'm misunderstanding your point)

Re: Where Human Sleep Went Wrong

#45
post #30

I think people in HN (and in general) have to remember the central axes of evolution before digesting this kind of article. I've already seen comments like it's "odd that no species has ended up evolving a continuous maintenance system" and "sleep has a higher opportunity cost in humans" in this comments section. This is a common, but poor framing of evolution. Remember: the only real rule with evolution is "did this…

I can see why it isn't a local or global maxima solving function, but it surely can be modelled by one, right?

Great question! It maybe can be, but what is the maxima that is being solved for exactly? There are usually tradeoffs, the most common and prevalent is our body's immune response. If it's under-active, we might die from an infection. If it's over-active, we get diabetes, lupus, chron's, and (probably) lots of mental health disorders.

So, it's a bit context dependent, and definitely dependent on other mutations that have occurred in other parts of your DNA. Most complex diseases are "polygenic", meaning it's a culmination of quite a few factors that would contribute to a specific good or bad outcome.

So, yes, it could be modeled as a sort very context dependent with a lot of highly correlated non-independent covariates. We do use quite a lot of statistical and ML methods to understand the genome (I work in statistical genetics), but the complexity of biology has so far proved a tough nut to crack.

Re: Where Human Sleep Went Wrong

#46
>18 degrees Celsius is considered optimal for sleep depth

I'm instantly skeptical of anyone making universal statements like this, because they're certainly not true for everyone, and having looked into these and similar (f/x "ideal room/office temperature"), are based on many entangled assumptions. Most of the time I expect it's just people making after-the-fact justification for doing (or imposing) what they most prefer.

Re: Where Human Sleep Went Wrong

#47
post #12

>the Hadza uniformly reported high satisfaction with their sleep. And why wouldn't they? This is (presumably) the only kind of sleep they know.

Also, they may not want to complain to strangers.

Also, we humans can get used to a lot of things and just be okay with it. For an extreme example, look at domestic abuse victims...

Re: Where Human Sleep Went Wrong

#48
post #30

Earlier quoted context omitted.

I can see why it isn't a local or global maxima solving function, but it surely can be modelled by one, right?

Great question! It maybe can be, but what is the maxima that is being solved for exactly? There are usually tradeoffs, the most common and prevalent is our body's immune response. If it's under-active, we might die from an infection. If it's over-active, we get diabetes, lupus, chron's, and (probably) lots of mental health disorders. So, it's a bit context dependent, and definitely dependent on other mutations that h…

Great answer! Thank you!

Re: Where Human Sleep Went Wrong

#49
post #38
post #30

Earlier quoted context omitted.

I can see why it isn't a local or global maxima solving function, but it surely can be modelled by one, right?

I'm a biologist so forgive me the poor wording, but there are "infinitely high" peaks/walls in the evolutionary landscape, as in: "the human urinary system has some evolutionary constraints and anatomical features that are not optimally designed from an engineering perspective, but they are generally functional and reflect our evolutionary history rather than deliberate design." So in that sense, a global maxima (min…

Interesting

I did not know human urinary tract was suboptimal.

Are there examples of "discontinuous" evolution where a chance mutation stumbled upon a much better way to do something that allowed a species to jump the gap?

I imagine it would be very rare because chance mutations in a single individual that confer extraordinary survival / mating advantage to offset entire population would be rare like being a superman among men.

Re: Where Human Sleep Went Wrong

#50
post #28
post #12

>the Hadza uniformly reported high satisfaction with their sleep. And why wouldn't they? This is (presumably) the only kind of sleep they know.

Do you really need to know other kinds of sleep in order to know if you feel like shit after waking up or if you feel fine?

If they have no frame of reference then it seems like their general contentedness is being measured (or as another commenter indicated, their willingness to gripe.)
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