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A 3D fruit fly on macOS desktop powered by the real FlyWire connectome

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Re: A 3D fruit fly on macOS desktop powered by the real FlyWire connectome

#32

I have no exposure to connectomes - or really anything quite like this (as opposed to good ol’ fashioned perceptrons) - so forgive my following uninformed question: Can someone explain if this software is ethical?

Why do you think it wont be?

Well, one obvious question is if the simulated brain experiences pain, or more generally can it suffer? And if so, how would we tell.

Re: A 3D fruit fly on macOS desktop powered by the real FlyWire connectome

#33

I have no exposure to connectomes - or really anything quite like this (as opposed to good ol’ fashioned perceptrons) - so forgive my following uninformed question: Can someone explain if this software is ethical?

> Can someone explain if this software is ethical? Probably not. People have been coming up with ethical frameworks for thousands of years and we have yet to come to a consensus. So it’s very unlikely that someone can say conclusively whether this is ethical or not, because that would require us to either 1) prove a single ethical framework is correct and then apply that framework to this software or 2) prove that un…

Honestly pretty funny that you gave a (fairly useless) metaethical answer instead of responding to the actual meaning, which was clearly soliciting ethical judgments about it.

Re: A 3D fruit fly on macOS desktop powered by the real FlyWire connectome

#37
post #22

Oh nice, might use this to create some art for my home. https://www.instagram.com/p/DMfi-9Vsl-u/ > Infinite Pain is a computer running a deterministic neural simulation of a microscopic nematode worm’s brain (c. elegans), subjected to regular pain stimuli.

are you ok ?

Re: A 3D fruit fly on macOS desktop powered by the real FlyWire connectome

#38

At some point in the future would it be possible to simply download a DNA sequence of an entire animal as a "ROM" and boot it into a virtual "reality"? What detail level of reality would we have to emulate for an egg to grow into an adult animal?

To give you a sense of the computation needed, a spatiotemporal physics simulation of a minimal (493 gene) bacterium's full 105 minute cellular cycle took 4-6 days of GPU hours on two A100s.

https://www.sciencedirect.com/science/article/pii/S009286742...

Compare this with a c elegens nematode: ~20000 protein coding genes and 959 cells, with all the extra machinery you'll find in a eukaryotic cell.

I'm reading this as both a question of raw simulation surface and combinatorics.

Re: A 3D fruit fly on macOS desktop powered by the real FlyWire connectome

#39

This is absolutely astounding. What an implementation. A connectome is like a full brain scan! I am asking Claude to port this to the browser and I'll host it, so you can try it without installing anything. Some details about the port: Claude is able to do porting tasks like this. I'll put up a link when you can try it in your browser. I was able to get it to port the complete BitNet b1.58 2-billion parameter model s…

It's pretty amazing stuff!

I was very excited the first time I saw a connectome as well. Years ago I managed to get most of openworm running and connected to some Lego Mindstorms to let the worm roll around my house. I'm not even sure the connectome was finished at that time.

Honestly, I barely had any idea what I was doing and we didn't have AI tools so I was never really sure what I wired to what. I did manage to hook... something to the ultrasound sensor and... another thing to the wheels so that when the sensor was triggered it would back up.

What blew my mind was the realization that these weird hybrid critters were probably the first true immortals. Now that we have a full connectome, who will bother with another? Students will probably just keep instantiating copies of this one to tinker with forever.

Re: A 3D fruit fly on macOS desktop powered by the real FlyWire connectome

#40
Would we be able to have a "digital human" when we reach the level of creating this kind of brain mapping for the human brain?

Honestly I think we're still discovering how powerful neural networks are and certainly they can do computations that sound very close to intelligence in some contexts, but I still find it hard to think that we can simplify the whole reality of an incredibly complex chemical machinery down to a bunch of matrices multiplications.

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