Live data from Hacker News

NIH is ending a key grant for budding clinical researchers

science.org

51–60 of 100 posts

Re: NIH is ending a key grant for budding clinical researchers

#51

Please understand that the goal of these policies is to weaken scientific research in the US. The people who push this stuff acknowledge openly that they oppose science, experts, and accurate information. This isn't a misunderstanding or a fumble.

They should be incentivizing researchers who have histories of publishing research that has been independently replicated. Way too much fraud going on that’s seeping into the real world.

Re: NIH is ending a key grant for budding clinical researchers

#52

Please understand that the goal of these policies is to weaken scientific research in the US. The people who push this stuff acknowledge openly that they oppose science, experts, and accurate information. This isn't a misunderstanding or a fumble.

My job depends on NIH continuing to function, but it is not immediately clear that this particular decision follows other worrying trends discussed here previously. Removing K-awards for clinical trials (but not regular, cheaper study formats) might simply be a recognition that clinical trials are too expensive for the K-format and conducting underpowered clinical trials does not help anyone much.

Re: NIH is ending a key grant for budding clinical researchers

#54
post #51

Please understand that the goal of these policies is to weaken scientific research in the US. The people who push this stuff acknowledge openly that they oppose science, experts, and accurate information. This isn't a misunderstanding or a fumble.

They should be incentivizing researchers who have histories of publishing research that has been independently replicated. Way too much fraud going on that’s seeping into the real world.

The fraud is the point with this administration.

Re: NIH is ending a key grant for budding clinical researchers

#55

Earlier quoted context omitted.

Big pharma is not like Bell Labs of old. Their researchers are expected to do work their bosses consider productive. They have no need for people who want to do curiosity-driven research and release the results to the public.

Big pharma is not like Bell Labs of old. Then maybe this is a sign that things should change back towards that direction.

Sure - but it's a moot point unless you're proposing plausible ways of achieving that, and that could be adopted by a movement with credible political power.

Re: NIH is ending a key grant for budding clinical researchers

#56
post #51

Please understand that the goal of these policies is to weaken scientific research in the US. The people who push this stuff acknowledge openly that they oppose science, experts, and accurate information. This isn't a misunderstanding or a fumble.

They should be incentivizing researchers who have histories of publishing research that has been independently replicated. Way too much fraud going on that’s seeping into the real world.

Frankly, this is a bit of an ignorant take.

1st, K-awards are specially meant to provide a funding path to support an early career scientist to continue in the field. Expecting that another team has already replicated the early work of a young scientist is not realistic. They are just starting out.

2nd. If you want replication, you got to fund replication. Researcher money doesn't appear out of nowhere, so make the decision, increase the science budget with a new replication budget.

3rd. Yes there is some fraud. Always has been. Is it more than before? Maybe? But unless you count paper mill journals that no serious scientist reads, it is much smaller than pop media makes it out to be.

Re: NIH is ending a key grant for budding clinical researchers

#57

Earlier quoted context omitted.

They are not similar types of research. It's like asking why Knuth doesn't do systems research for a social network or advertising company. Eddy's lab builds the tooling and concepts that everyone else uses throughout the field in foundation upon which new discoveries are built. There's no commercial funding for that sort of work, and I'm honestly shocked at the lack of understanding of this is Silicon Valley. Nobody…

I see what you're saying, and think it makes sense. Anecdotally, Apple (thinking different(ly)?) ran at least two pure research inner groups that i was in contact with when I was in engineering at Apple; to your point, I have no sense of impact on profits from doing that.

Sometimes an organisation has what I would call "Vanity Hires". People hired not because they really make much sense as part of the organisation but because their celebrity "rubs off" on the org by association.

These can be very transactional, they take your money and if they have a notional place of work (not so necessary in the era of WFH) you give them a broom closet somewhere as an "office" which they will never visit.

Or at the other end of the spectrum they try to actually be helpful, perhaps because they actually did want to do whatever it is you wrote on the hiring paperwork, and this might even be a productive relationship, at worst it's a distraction for anybody whose interest you've struggled to maintain and don't want to let go. Hey, go help uh, Doctor Frankenstein with his project to (checks notes) invent a new machine to replace Geese for some reason.

Given Apple's wealth I'd expect some mix of "Vanity Hires" and people who really are expected to do important strategic work for the $$$. As I described, to some extent you can't tell. If you've never heard of them, maybe that's just because you don't know their area of expertise, and equally even if they seem to be working their backside off, maybe they're just like that and Apple was astonished that they actually showed up and started working.

Re: NIH is ending a key grant for budding clinical researchers

#58
post #3

It's hard to overstate how chaotic and mismanaged NIH has been in the past two years. Sufficiently advanced incompetence is indistinguishable from malice, so it's hard to impute motives here. A lot of labs are being defunded for no good reason, losing researchers, losing the thread, and putting entire directions of useful research on ice, likely forever. There are some clear indications of where it is pure malice and…

I'm going to call it malice. Either way the people running the government now are the avowed enemies of functioning institutions. No need to give these freaks the benefit of the doubt. (See Russ Vought's comments about putting all government workers in trauma just for one and he's head of OMB.)

It's not the regulars at NIH. If anything they are pulling more unofficial overtime than ever before to try to compensate for what is coming from on top and what DOGE destroyed

Re: NIH is ending a key grant for budding clinical researchers

#59

Please understand that the goal of these policies is to weaken scientific research in the US. The people who push this stuff acknowledge openly that they oppose science, experts, and accurate information. This isn't a misunderstanding or a fumble.

Can anyone explain the reasoning behind it? I can understand (not saying I approve) targeted opposition to specific scientific claims to favor commercial interests (climate change denial to favor oil & gas, etc), but wouldn't a general anti-science movement make the country less competitive in the long run and directly hurt industries like pharma/etc?

> wouldn't a general anti-science movement make the country less competitive in the long run

Less competitive for tertiary industries like tech, pharma, etc. More competitive for lower-level industries like mining, resource extraction, low-tech and labor-intensive manufacturing, etc. The Administration represents the latter economic sectors. They want more people in factories and fewer people in offices.

Re: NIH is ending a key grant for budding clinical researchers

#60

We're seeing a generational loss of young talent that will be hard to reverse. PhD grads who would normally stay in the US after graduation are returning to their home countries. My American post-doc friends have had funding for cancer research, Alzheimer's research, Parkinson's disease; some have left the US, others are making plans to do so. And for what? Any money we "saved" by killing our research pipeline has al…

Presumably for the transition of biotech from the US to somewhere else. I don't know what kind of favor buys you the sabotage of an industry, but it must've been a good one.
Post reply on HN