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Semaglutide linked to lower predicted dementia risk

alz-journals.onlinelibrary.wiley.com

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Re: Semaglutide linked to lower predicted dementia risk

#331

Post by rootusrootus »

swalsh wrote: post #327
antonmks wrote: post #21

Absolutely magical drug ! It makes you thinner, younger and now smarter !

For as long as you're on it, but eventually you run out of body fat.

Even at the max dose you will hit a spot where you stop losing weight before you get anywhere near running out of body fat. Some people even go off label stacking two or more or cranking the dose past officially supported levels because they still are overweight.

People honest with themselves will understand that it’s a chronic treatment, you don’t stop.

Re: Semaglutide linked to lower predicted dementia risk

#332

Post by jnovek »

owebmaster wrote: post #324
acuteaura wrote: post #323

Earlier quoted context omitted.

There is a fine line between being opposed to fat acceptance and thinking performative cruelty works. (It's does not. It made me so much worse. I have nothing but bad things to say about the medical "professional" who catastrophized my diagnosis to "wake me up" and then shrugged when my response was depressed resignation.)

You can't depend on people being nice to take care of your own health.

There are several studies now showing that symptoms reported by overweight patients are taken less seriously by medical professionals, it’s not just a matter of people “being nice”. It’s actually providing a lower standard of care.

Re: Semaglutide linked to lower predicted dementia risk

#333

Post by Lagoon3384_SWE »

Very american thread and comments.

At most I was 24 BMI and I felt like a fat bastard during COVID. Work from home in sweatpants and I got up to 24 BMI. 77-78kg, 182cm. I just did not weigh myself so I actually did not notice I had gained! But I did and decided to do something about it.

But I lost the weight pretty quickly.

I grew up at 60-65kg and that is where I feel at home in my body. I feel like myself basically. I should add I am 35, so certainly no spring chicken.

"omg how did you lose it"

Very easy.

1. Weight loss is done through diet, not exercise. Exercise is great for the body, but not a primary weight loss.

2. If you work an office job you do not need 3 full meals a day. Eat a light breakfast, a full lunch and a light meal for dinner.

3. On the weekends, fast. If you are committed, this weekend, buy like 4-5 litre of sugar free/diet soda, flavoured water zero calories, and caffeine pills. To distract yourself, play a high dopamine grind game like Diablo IV, PoE, Borderlands, WoW/FFXIV, CS, Valorant etc.

Just drink, do not eat. Hunger is temporary and will last like 1h for me, then the body "gives up". Do a 24h or 48h water fast, you will drop 5kg easy and feel way less bloated. Repeat next weekend...

Set an alarm every 2-3h to get up and walk. Get your 10k steps in everyday by walking outside.

"omg that's unhealthy"

Yes, ofc but it is more healthy than being overweight or close to overweight, agreed?

"you can only do this because ur a Swedish chad and you have walkable cities!!"

I'm a degenerate gamer. lol

Re: Semaglutide linked to lower predicted dementia risk

#334

Post by Lagoon3384_SWE »

throwaway82931 wrote: post #110
londons_explore wrote: post #23

So has anyone managed to separate the effects of semaglutide from the effects of weight loss? If this is caused by the weight loss, it is a little disappointing that public health didn't act quicker - lots of people have been overweight for a century now, so literally 10's of millions of people could have been saved from dementia had action been taken 100 years ago.

All my immediate family members are obese. I'm not (BMI 24.5, borderline overweight at the high end of normal, highest lifetime BMI was 29.5), but that's through strenuous, exhausting effort over decades. I also exercise regularly, though I've learned over time how disconnected exercise is from weight management. At my weight, I'm not a candidate for going on a GLP-1. I'm sure I could find an unethical doctor to pres…

Very american thread and comments.

At most I was 24 BMI and I felt like a fat bastard during COVID. Work from home in sweatpants and I got up to 24 BMI. 77-78kg, 182cm. I just did not weigh myself so I actually did not notice I had gained! But I did and decided to do something about it.

But I lost the weight pretty quickly.

I grew up at 60-65kg and that is where I feel at home in my body. I feel like myself basically.

I should add I am 35, so certainly no spring chicken.

"omg how did you lose it"

Very easy.

1. Weight loss is done through diet, not exercise. Exercise is great for the body, but not a primary weight loss.

2. If you work an office job you do not need 3 full meals a day. Eat a light breakfast, a full lunch and a light meal for dinner.

3. On the weekends, fast. If you are committed, this weekend, buy like 4-5 litre of sugar free/diet soda, flavoured water zero calories, and caffeine pills. To distract yourself, play a high dopamine grind game like Diablo IV, PoE, Borderlands, WoW/FFXIV, CS, Valorant etc.

Just drink, do not eat. Hunger is temporary and will last like 1h for me, then the body "gives up". Do a 24h or 48h water fast, you will drop 5kg easy and feel way less bloated. Repeat next weekend...

Set an alarm every 2-3h to get up and walk. Get your 10k steps in everyday by walking outside.

"omg that's unhealthy"

Yes, ofc but it is more healthy than being overweight or close to overweight, agreed?

"you can only do this because ur a Swedish chad and you have walkable cities!!"

I'm a degenerate gamer.

Re: Semaglutide linked to lower predicted dementia risk

#336

Post by jnovek »

jvidalv wrote: post #317
cloudie78 wrote: post #311

Earlier quoted context omitted.

It’s in broad terms weight loss related. More specifically blood glucose and insulin regulation which can be out of whack even if you’re not diabetic on paper. This is why you’ll see people claiming they’re not diabetic but still saw improvement from Ozempic and friends. Their insulin and glucose regulation was spoke. in casual terms “fucked”. GLP-1 receptor agonists such as semaglutide act partly through the brain t…

[flagged]

I think you’re misunderstanding the fat acceptance movement. It’s about separating the illness from the person, not about obesity health. In our society it would be impossible to be unaware that obesity is unhealthy.

People go out of their way to be mean to fat people. The fat acceptance movement is essentially “please don’t do that”.

Re: Semaglutide linked to lower predicted dementia risk

#337

Post by Lagoon3384_SWE »

01100011 wrote: post #38

I'm a big semaglutide proponent after being on it for a year. I know research says it helps with inflammation, arthritis (separately from weight reduction), and all sorts of magical things. I lost 40 pounds in a year(230 to 190) at age 50. Great! I also went from being active and fat(weightlifting with some cardio) to basically having no energy. In the last year I've had arthritis appear in several joints. I'm awake…

Good that someone speaks up on the side effects.

As a slim person naturally, I see these drugs as cheating and I hope they are all not good.

We need some markers for separation, clothes are another good one. I am "dressed up" for wearing chinos and an OCBD lol.

Re: Semaglutide linked to lower predicted dementia risk

#338

Post by owebmaster »

jnovek wrote: post #332
owebmaster wrote: post #324

Earlier quoted context omitted.

You can't depend on people being nice to take care of your own health.

There are several studies now showing that symptoms reported by overweight patients are taken less seriously by medical professionals, it’s not just a matter of people “being nice”. It’s actually providing a lower standard of care.

There are several studies now showing that recommendations like "losing weight" are taken less seriously by overweight patients.

Re: Semaglutide linked to lower predicted dementia risk

#339

Post by cthalupa »

simianparrot wrote: post #300
OptionOfT wrote: post #158

Earlier quoted context omitted.

We're too soft on companies, but equally too hard on people who have a food addiction.

[flagged]

Except this entire narrative is thrown off by the fact that obesity has been a problem before any of that and is a problem in countries without any of that. Even places like Korea where you are literally shamed constantly by friends and family for being even remotely overweight has obesity growing all while having basically the exact opposite culture of what you are complaining about.

Basically the only developed country where overweight and obesity have stayed flat is Japan.

Re: Semaglutide linked to lower predicted dementia risk

#340

Post by david-gpu »

Lagoon3384_SWE wrote: post #333

Very american thread and comments. At most I was 24 BMI and I felt like a fat bastard during COVID. Work from home in sweatpants and I got up to 24 BMI. 77-78kg, 182cm. I just did not weigh myself so I actually did not notice I had gained! But I did and decided to do something about it. But I lost the weight pretty quickly. I grew up at 60-65kg and that is where I feel at home in my body. I feel like myself basically…

I used to be similarly judgemental and flippant when my BMI was 20~21 in my 20s and 30s.

My health took a few wrong turns and I now have a BMI of 30. My diet is just as good, if not better, than back when I was slim. But now my sleep is worse, I tire much more easily, recover much worse from exercise, and, crucially, I am much hungrier.

I no longer preach how simple it is to maintain a healthy weight. I should have known better back then and kept my mouth shut.

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