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At-home test for infected ticks could improve Lyme Disease diagnosis

smithsonianmag.com

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Re: At-home test for infected ticks could improve Lyme Disease diagnosis

#81
post #68
post #55

Earlier quoted context omitted.

CDC recommendation is more interested in preventing antibiotic resistance than in preventing Lyme disease for the patient. Obey CDC at your own risk

Antibiotics aren't free of risks to the patient either, including doxycycline. There's always a risk tradeoff.

100%. CDC is not a replacement for a trusted doctor

Re: At-home test for infected ticks could improve Lyme Disease diagnosis

#82

If not this, then what? Like others, I was interested in the article because of Lyme and other diseases. Ticks really do suck. I appreciate all the science-y comments though I understand very little. I appreciate comments about personal experiences with ticks, getting bitten, and getting sick. I’m left with this: If this test is not really a viable solution (or at least one solution) to the problem of the unaffordabi…

Growing up near the epicenter of Lyme disease (which is awful) - it’s not that hard to deal with on a regular basis (I probably take half a dozen plus attached ticks off me year. When your pre-in-post shower - tick check. Take them off, worried they were on for a while, doxycycline as prophylactic. Feel crappy afterwards doctor+blood test / maybe antibiotics. It sucks but it’s manageable. Bourbon virus and alpha gal are super scary. When you k ow about them it’s easier to manage - when you’re oblivious it’s when it’s really dangerous.

What would be way more useful is a quick blood test (pin prick type à la thernos) that could diagnose early for treatment.

Re: At-home test for infected ticks could improve Lyme Disease diagnosis

#83
post #2

Wow, this seems a pretty big deal. Here in the UK, Lyme traditionally been a marginal problem (tick bites aren't) but we now have such rapid climate change, along with rapidly increasing wild deer and boar populations, that some areas in the UK are becoming risk zones on more or less the same level of risk as some US regions. Alas the difference here is that education has not caught up to the USA: very few people hav…

It started around Connecticut in the 70s and has been spreading out radially since then. I believe it’s still not a huge problem in the western United States (there are other tick borne diseases there however). Soon it will spread across the world and tick bites will be serious business everywhere.

Correct. The outbreak was first recognized in 1975 in Old Lyme, Connecticut, directly across the Long Island Sound from the Plum Island Animal Disease Center (a lab which had been doing explicitly offensive biological weapons research until at least 1969), which led to an unverified theory about an escaped bioweapon.

Genetic studies and museum tick specimens prove the bacteria existed in North America for thousands of years before the lab was built. Whether there was gain of function done on it is not publicly verified.

Re: At-home test for infected ticks could improve Lyme Disease diagnosis

#84

Why test ticks for Lyme Disease? Make a cheap, accurate test for Lyme disease in humans ! Jeez! Chasing ticks, c'mon, really, my f*ing intelligence is insulted by the suggestion.

Yeah - I just want to know early that I need to start treatment not “I might be infected”

Re: At-home test for infected ticks could improve Lyme Disease diagnosis

#85
post #69

There are MANY facebook groups filled with people fully convinced that they have Lyme disease. These groups teach that virtually any and every symptom is caused by the infection and that basically everyone has it. As if this wasn’t insane enough, the people in the group will push each other to go on antibiotics - via so called lyme literate doctors - until they are on the verge of death due to the side effects. Worse…

We are quickly entering a medical dark age due to the conspiracy theorists, “Do Your Own Research-ers,” YouTube influencers, and other kinds of Internet-borne DIY self diagnosis.

Re: At-home test for infected ticks could improve Lyme Disease diagnosis

#86

Earlier quoted context omitted.

It started around Connecticut in the 70s and has been spreading out radially since then. I believe it’s still not a huge problem in the western United States (there are other tick borne diseases there however). Soon it will spread across the world and tick bites will be serious business everywhere.

Correct. The outbreak was first recognized in 1975 in Old Lyme, Connecticut, directly across the Long Island Sound from the Plum Island Animal Disease Center (a lab which had been doing explicitly offensive biological weapons research until at least 1969), which led to an unverified theory about an escaped bioweapon. Genetic studies and museum tick specimens prove the bacteria existed in North America for thousands o…

I live near Plum Island. Just look at the Google Map reviews to get an idea of the sentiment. Camp Hero, Plum Island…lotta material for Netflix series coming out of Long Island.

Re: At-home test for infected ticks could improve Lyme Disease diagnosis

#87
post #2

Wow, this seems a pretty big deal. Here in the UK, Lyme traditionally been a marginal problem (tick bites aren't) but we now have such rapid climate change, along with rapidly increasing wild deer and boar populations, that some areas in the UK are becoming risk zones on more or less the same level of risk as some US regions. Alas the difference here is that education has not caught up to the USA: very few people hav…

Ah, yes, climate change, which also explains how Lyme disease, first diagnosed in the US in the northern midwest and northeast, later spread southward. I'm sure it works in mysterious ways in your neighborhood as well.

Re: At-home test for infected ticks could improve Lyme Disease diagnosis

#89
post #25

Unfortunately, there are major issues with this approach. The vendor claims "lab-level accuracy" (conveniently omitting the actual accuracy numbers), but the test is a lateral flow test, which means its Limit of Detection is going to be orders of magnitude worse than molecular tests. Tick tests do not require FDA clearance, so their claims are most likely unreviewed. Existing lab tests for ticks are almost universall…

It's been 15 years since I worked on open source PCR machines, but has someone not figured out how to build a "one time use" disposable type qPCR test? A single test, not an instrument. There's no way these types of tests should be left up to lateral flow etc.
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