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Could psilocybin be the key to treating anorexia?

scientificamerican.com

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Re: Could psilocybin be the key to treating anorexia?

#61

Post by inigyou »

salemh wrote: post #47
mikert89 wrote: post #22

Earlier quoted context omitted.

anyone i have met that did Psychedelics more than a few times, permanently changed their brain chemistry in a way that was obvious. sure they dissolve some kind of prison, but many people never make it back from that dissolution and end up somewhere worse

Co-signed here with psilocybin being dangerous based on direct personal experience, and seeing inumerable issues with party friends. Apologists of psylocybin will sometimes say 'its not as harsh and dangerous as LSD.' Ok, damaging effects of this drug are always apologized away and covered up. The biggest problem with psilocibyn is people are told its benign, then they go on a 'trip', and sometimes in their come-down…

If you're a real person, you've been shadowbanned since 2021 and don't seem to have noticed.

Re: Could psilocybin be the key to treating anorexia?

#62

Post by MSFT_Edging »

deburo wrote: post #50
MSFT_Edging wrote: post #19

Earlier quoted context omitted.

Yeah, Disenfranchise the hippies and the blacks by targeting those communities with heavy policing. Sorta like today where there's similar drug use levels between white and black populations, but one side is more heavily policed than the other.

Perhaps you'd like to dig down into the stats using AI to find out that the gap in policing isn't really due to race. Check by poverty level, and perhaps by geographic areas.

I was trying to hide my power level but yeah, the point is to maintain a permanent "underclass" that can't pick and choose what work they take.

If everyone was truly free, we'd have to pay the real price to clean up shit and that would mean an inversion of our pyramid scheme.

Re: Could psilocybin be the key to treating anorexia?

#63

Post by bossyTeacher »

inigyou wrote: post #52
bossyTeacher wrote: post #46

Earlier quoted context omitted.

Surely, that's dosage dependent and frequency dependent. One per week vs once every three months vs once per year. Low dose vs medium dose vs high dose. Plus, these things are illegal which means that most of the time you are not getting the real but instead pharmacologically similar substances that might have secondary effects. This is way you can't reliably imply a correlation because it is a black market and often…

Pills and white powders get mixed up and adulterated that way, but I think everyone who eats mushrooms and hallucinates ate the right mushrooms. LSD is sometimes but rarely substituted for other hallucinogenic drugs that can be delivered on blotter paper, of which there aren't many.

>I think everyone who eats mushrooms and hallucinates ate the right mushrooms

That's a tautology. But what you meant is not true. Some of the compounds are chosen because they are chemically similar and have psilocybin like effects. Even if you were to test this with a standard kit it would be classified as psilocybin. Your average consumer would be none the wiser. The reason these compounds exist is literally because of that very reason. They were made in the context of slow moving policies targeting psychedelics by listing specific compounds.

Re: Could psilocybin be the key to treating anorexia?

#64

Post by ASalazarMX »

inigyou wrote: post #2

Psychedelics open your brain up to rewiring in some way, and can be used under direction to treat a lot of things. But of course, people who didn't like the Vietnam War used them recreationally, which is why the US government made them globally illegal.

Every time I see "does {PSYCHEDELIC} cure {AILMENT}" studies, I fear a recreation of the opioid crisis. They need to be studied as a treatment, yes, but people, doctors, and pharmaceuticals will abuse them given the opportunity and lack of oversight.

Re: Could psilocybin be the key to treating anorexia?

#65

Post by jdietrich »

Taronar wrote: post #43
jdietrich wrote: post #33

Sorry, but the answer is almost certainly no. We now have good quality data on psylocybin as a treatment for depression; at best, it's slightly more effective than existing treatments, at the cost of a small but significant increased risk side-effects (primarily severe acute anxiety and psychosis, possibly HPPD). We have less data on other psychedelics and other conditions, but none of it looks spectacular when you t…

This is a treatment that can help people. just because it didn't help you does not mean it's ineffective in totality which is the stance you seem to take.

The question posed is "Could psilocybin be the key to treating anorexia?". Psychedelics are effective in treating some psychiatric disorders - I've been clear about that - but they are (at best) only marginally more effective than most existing treatments. That's a good thing, it will help some patients, but it's a million miles from being the key treatment.

Re: Could psilocybin be the key to treating anorexia?

#66

Post by jdietrich »

virgil_disgr4ce wrote: post #31
mikert89 wrote: post #22

Earlier quoted context omitted.

anyone i have met that did Psychedelics more than a few times, permanently changed their brain chemistry in a way that was obvious. sure they dissolve some kind of prison, but many people never make it back from that dissolution and end up somewhere worse

> did Psychedelics more than a few times If you want to specify LSD, you should do that, not "psychedelics." There are many, many psychedelics. They have sometimes radical differences. You cannot generalize that word into "many people never make it back." That is flat-out wrong, not to mention harmful.

>There are many, many psychedelics. They have sometimes radical differences.

Psilocybin is a more selective 5-HT2A agonist than LSD and is more rapidly metabolised. At normal recreational or clinical doses, they really aren't very different. LSD isn't quite as well-researched as psilocybin as a psychiatric drug, but the data we have suggests that it isn't meaningfully different in terms of risks or benefits.

Re: Could psilocybin be the key to treating anorexia?

#67

Post by inigyou »

ASalazarMX wrote: post #64
inigyou wrote: post #2

Psychedelics open your brain up to rewiring in some way, and can be used under direction to treat a lot of things. But of course, people who didn't like the Vietnam War used them recreationally, which is why the US government made them globally illegal.

Every time I see "does {PSYCHEDELIC} cure {AILMENT}" studies, I fear a recreation of the opioid crisis. They need to be studied as a treatment, yes, but people, doctors, and pharmaceuticals will abuse them given the opportunity and lack of oversight.

Psychedelics aren't even remotely addictive. People who take them usually don't want to take any more of them for months.

Re: Could psilocybin be the key to treating anorexia?

#68

Post by inigyou »

bossyTeacher wrote: post #63
inigyou wrote: post #52

Earlier quoted context omitted.

Pills and white powders get mixed up and adulterated that way, but I think everyone who eats mushrooms and hallucinates ate the right mushrooms. LSD is sometimes but rarely substituted for other hallucinogenic drugs that can be delivered on blotter paper, of which there aren't many.

>I think everyone who eats mushrooms and hallucinates ate the right mushrooms That's a tautology. But what you meant is not true. Some of the compounds are chosen because they are chemically similar and have psilocybin like effects. Even if you were to test this with a standard kit it would be classified as psilocybin. Your average consumer would be none the wiser. The reason these compounds exist is literally becaus…

I was under the impression that people ate dried mushrooms, not pure psilocybin extract? Are they sprinkling supermarket mushrooms with these other chemicals?

Re: Could psilocybin be the key to treating anorexia?

#69

Post by joquarky »

mikert89 wrote: post #22
an0malous wrote: post #11

Earlier quoted context omitted.

Psychedelics desolve the conceptual prison your mind is in, the government made them illegal because they build those prisons. Charitably, you could argue a functional society involves some amount of indoctrination into a set of shared beliefs and a large percentage of people losing that indoctrination would destroy society. Could the US function if everyone was a pacifist, anti-capitalist, hippie? I think that was a…

anyone i have met that did Psychedelics more than a few times, permanently changed their brain chemistry in a way that was obvious. sure they dissolve some kind of prison, but many people never make it back from that dissolution and end up somewhere worse

They "never make it back" to what exactly?

What are you using as attributes to form a judgement of what is "worse"?

Re: Could psilocybin be the key to treating anorexia?

#70

Post by joquarky »

bossyTeacher wrote: post #46
mikert89 wrote: post #37

Earlier quoted context omitted.

unfortunately, I think repeated psychedlic use has deterministic and predictable changes to peoples personalities. its not some "awakening", its a structural change in the brain. i watched many close friends fade away after too much use

Surely, that's dosage dependent and frequency dependent. One per week vs once every three months vs once per year. Low dose vs medium dose vs high dose. Plus, these things are illegal which means that most of the time you are not getting the real but instead pharmacologically similar substances that might have secondary effects. This is way you can't reliably imply a correlation because it is a black market and often…

They're not illegal everywhere.

You can grow mushrooms from spores and quality control the whole process.

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