Even if smoking didnt cause cancer it would still be terrible. 6 months since i quit using nic gums.
good job!
Why DNA damage from smoking and UV rays cause cancer in some but not others
81–90 of 119 posts
Re: Why DNA damage from smoking and UV rays cause cancer in some but not others
#82F* cancer. On my mother's side, her mom and sister died of breast cancer, her other sister caught it early, her brother died of cancer (throat or lung, not sure). She removed her breast 20 years ago at almost 50, went through chemo and radiotherapy, she was a survivor, cured. Just a month ago got headaches and turns out new brain tumor. Neurosurgeons removed it, but against all odds nothing to do with the old cancer,…
We all die eventually. All you can do is live your best life. Unfortunately we don't all get the same hand from the dealer.
Re: Why DNA damage from smoking and UV rays cause cancer in some but not others
#83As a millennial growing up it was beaten into our head that smoking was a death sentence. I recently looked up what the actual cancer rate among smokers was... about 125k people in the US die of lung cancer annual. 25 million people smoke annually. That is a 0.5% chance for occasional smokers. Even if you smoke a pack a day your entire life, the cancer rate is less than 15%. I am in no way saying it is okay to smoke,…
Cigarettes kill about 480,000 people in the US annually. Lung cancer isn't the only kind of cancer you get from smoking cigarettes, and cancer isn't the only way it can lead to your death, so it seems very strange to only pay attention to lung cancer here.
You don't need lung cancer to have an absolutely miserable decline and death from COPD, for example.
https://archive.cdc.gov/www_cdc_gov/tobacco/data_statistics/...
Re: Why DNA damage from smoking and UV rays cause cancer in some but not others
#84Earlier quoted context omitted.
I'm pretty light skinned and the burn pretty easily. I just put on sunscreen by default when going hiking/mountain biking. I'm really excited for the new sunscreens coming out here in the US that have those new to us ingredients that the Euro's have had forever.
Agreed completely. I also leverage sun shirts quite a bit.
I discovered sun shirts very recently, with a hood. It's so much nicer to slip it on than apply sun block, which I'm trying to reduce since I don't really want it in my blood stream [1]. Mine is white, so I usually end up a bit cooler than without!
[1] https://jamanetwork.com/journals/jama/fullarticle/2733085?gu...
Re: Why DNA damage from smoking and UV rays cause cancer in some but not others
#85Glad, so I can continue smoking :-))
Re: Why DNA damage from smoking and UV rays cause cancer in some but not others
#86Is there any info for a way to check this on your SNPs from genome sequencing data?
Re: Why DNA damage from smoking and UV rays cause cancer in some but not others
#87F* cancer. On my mother's side, her mom and sister died of breast cancer, her other sister caught it early, her brother died of cancer (throat or lung, not sure). She removed her breast 20 years ago at almost 50, went through chemo and radiotherapy, she was a survivor, cured. Just a month ago got headaches and turns out new brain tumor. Neurosurgeons removed it, but against all odds nothing to do with the old cancer,…
If incidences of cancer of any type are 1 in 100,000 for the population at large, then generally any slice of that population will have similar odds. Which includes people with cancer.
So those who already have cancer, have a chance to develop a second cancer.
It is very not fair.
Re: Why DNA damage from smoking and UV rays cause cancer in some but not others
#88Earlier quoted context omitted.
Just so you know, burning & cancer isn't the only reason to avoid strong sunlight - it also causes skin aging (i.e. wrinkles). If you don't want to be super wrinkly when you're old, wear suncream!
When we were dating, the first thing my now wife did was get me on a regimin of sunscreen and tretinoin. I now have significantly fewer wrinkles than my younger siblings (2-3 years).
I'd be wary of that! Tretinoin has been linked to birth defects in women and they are warned against it. I wouldn't trust it for the father either.
Re: Why DNA damage from smoking and UV rays cause cancer in some but not others
#89F* cancer. On my mother's side, her mom and sister died of breast cancer, her other sister caught it early, her brother died of cancer (throat or lung, not sure). She removed her breast 20 years ago at almost 50, went through chemo and radiotherapy, she was a survivor, cured. Just a month ago got headaches and turns out new brain tumor. Neurosurgeons removed it, but against all odds nothing to do with the old cancer,…
We all die eventually. All you can do is live your best life. Unfortunately we don't all get the same hand from the dealer.
A grade 4 glioma doesn't even give you a fighting chance, there is only survival from months to maybe over a year.
Re: Why DNA damage from smoking and UV rays cause cancer in some but not others
#90Earlier quoted context omitted.
When we were dating, the first thing my now wife did was get me on a regimin of sunscreen and tretinoin. I now have significantly fewer wrinkles than my younger siblings (2-3 years).
I'd be wary of that! Tretinoin has been linked to birth defects in women and they are warned against it. I wouldn't trust it for the father either.
This is a common misconception. Topical tretinoin has been shown to have no effect on the fetus. Oral tretinoins (like isotretinoin) have been linked to congenital defects. This is due to the differing rates of absorption and the resulting ability for the retinoid to cross the placenta at higher concentrations.
With that said, folks who are pregnant are discouraged from using any retinoids out of an abundance of caution.