New HIV vaccine shows unprecedented success in preclinical study

Post by mrguyorama » Tue, Jul 28, 2026, 5:47 PM UTC

MostlyStable wrote: post #99

epistasis wrote: post #92

Earlier quoted context omitted.

Which is in fact panic that teens are not having enough children, because that's where we have seen big drops... This whole "panic" seemed weird from the start, but once it becomes clear that it's from the lack of teen pregnancies it takes on an even creepier Epstein-like oddness.

It is entirely possible to believe multiple things at once: 1. The drop is fertility is bad for society 2. The drop in teen pregnancy is good, despite it's contributions to 1 3. We should try to fix 1. without undoing 2.

Post by tallanvor » Tue, Jul 28, 2026, 5:53 PM UTC

simonask wrote: post #40

cogman10 wrote: post #17

Earlier quoted context omitted.

It's a solved problem if you are someone that knows you'll be exposed to HIV in the very near future and you have the money and wherewithal to purchase PrEP before that event (and you can plan the event 7 days out). The power of a vaccine is you can give it to adults and kids before they are sexually active and protect them, potentially, for the rest of their lives. I'd also be curious to know if the combination of A…

Ad-hoc use of PrEP just requires that you take a double dose 1 hour prior to potential exposure, and follow up with another double dose 24 hours later, at least with the versions commonly prescribed to sexually active groups in my area. I agree that a vaccine is another game-changer, but it’s extremely important that we don’t spread misinformation about the efficacy and convenience of PrEP. In developed societies, it…

Post by hydrogen7800 » Tue, Jul 28, 2026, 5:59 PM UTC

shevy-java wrote: post #151

iandanforth wrote: post #20

The most interesting point of the article for me is that this vaccine appears to be a series of shots which act as a curriculum for the immune system. Each one slightly different and targeting a different stage of B-cell development. I've never thought of vaccine series working like that, so it was a new and impressive idea.

I do not see what is impressive here at all. The immune system constantly yields new antibodies targeting different epitopes - all the time. THAT is what is impressive, not multi-vaccines trying to induce shifts towards certain epitopes over others.

Post by BizarroLand » Tue, Jul 28, 2026, 6:02 PM UTC

sarchertech wrote: post #173

jimbob45 wrote: post #170

Earlier quoted context omitted.

No, there will always be the threat of teen pregnancy. Conversely, we could wipe out HIV permanently if enough public will across the world was directed toward it. I fully believe that HIV wouldn’t exist if PrEP had come out in the 80s when public hysteria was at an all-time high and the will to eradicate it was present.

We haven’t even managed to wipe out polio, and that is a cheap, lifelong vaccine.

Post by camphy » Tue, Jul 28, 2026, 6:07 PM UTC

vasco wrote: post #125

camphy wrote: post #101

Earlier quoted context omitted.

> Is someone irresponsible enough to pursue causal, unprotected sex with random partners also likely to be responsible enough to visit a doctor proactively and comply with a prep regimen? Yeah, me. What a wild statement to make. It’s a big world out there, my friend.

You may have missed the word likely.