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Does creatine make you smarter?

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Re: Does creatine make you smarter?

#131
post #99
post #51

Earlier quoted context omitted.

I get severe muscle cramping, even after pounding water and electrolytes. Like I can’t handle my kid something in the car without risking a spasm.

Do you lift weights?

Yes I’m fit, easily passed military and LEO fitness tests this year.

Re: Does creatine make you smarter?

#132
post #51

Earlier quoted context omitted.

I get severe muscle cramping, even after pounding water and electrolytes. Like I can’t handle my kid something in the car without risking a spasm.

spasms are commonly a potassium deficiency, you could take a multivitamin.

I do function health and have completely normal nutrient blood levels.

Re: Does creatine make you smarter?

#133
post #124

Earlier quoted context omitted.

It’s always been popular among athletes and weight lifters but now nootropic influencers have gotten ahold of it. It’s one of the few supplements with robust scientific evidence of a strong effect but that’s in athletic performance not nootropics.

and that scientific evidence is new? like a new study boosted this or just resurfacing?

[deleted]

Re: Does creatine make you smarter?

#134
post #63

Earlier quoted context omitted.

Personally I take creatine for entirely non-cognitive reasons, so it's reassuring to know it's probably not making me any dumber.

Though you also have to consider potentially adulterated powder (accidental or not) in the unregulated supplement industry. That's why I dropped creatine since I didn't notice any benefits when I tried it for a year.

There is a brand of creatine manufactured in the US (con-cret) and a brand manufactured in Germany (Creapure). Either of those companies should address the concern around adulterated powder.

> That's why I dropped creatine since I didn't notice any benefits when I tried it for a year.

Some percentage of people (~20%) are creatine non-responders [1]. It's pretty reasonable to try creatine and then drop it if you find no benefit. I personally find the gain very marginal.

[1] https://fitchef.com/shorts/creatine-non-responder/

Re: Does creatine make you smarter?

#135
I have definitely noticed improvements taking a larger dose with my energy when low on sleep, check out McMorris et al. (2006) which is not cited here. I agree it probably doesn't make you generally more 'smart' but it does may improve function under stress, e.g. when sleep deprived, also see Gordji-Nejad et al. (2024). I think the sleep benefits should at least be mentioned in this article.

Also search for 'sleep' in this comment section, seems many see similar improvements!

Re: Does creatine make you smarter?

#136
post #64

Earlier quoted context omitted.

I wasn't expecting creatine to have any bearing on my emotional state in the first place, so I'm not sure how that would work.

Knowledge of the potential is peripheral expectation. If you can say "Oh yea that makes sense" with the same set of knowledge you had both before and after some event happens, all else being equal, you have an expectation. That is enough for placebo. You have to have literally 0 knowledge about an event to rule out placebo.

Are you suggesting that the placebo effect applies retroactively? I'd been using creatine for months before I even heard there were conversations about supposed cognitive effects (and I hadn't noticed any myself, either, and I continue to not notice any. That isn't why I take it.)

Re: Does creatine make you smarter?

#137

Earlier quoted context omitted.

Productivity isn’t the only reason to be smarter. For example, there’s also the benefit of asking fewer inane questions on the internet (hypothetically)

Present company excluded, of course.

I still seek the fount of infinite wisdom.

Re: Does creatine make you smarter?

#138
post #30

Earlier quoted context omitted.

Health fads come and go

Creatine is a health fad? No other supplement has been this widely-used for such a long time. It was considered safe and effective when I started using it 30 years ago. The benefits are/were well established, the mechanisms well-known, the safety is impeccable. If anything, it's the most well-established supplement on the market - the exact opposite of a fad!

OP was asking why the attention now though specifically. I'm not calling it quackery, etc.

Re: Does creatine make you smarter?

#139

The conclusions aren't any different (it's one of the few thing that helps strength, poses no danger to your hair, and almost certainly does nothing for cognition), but the articles at https://www.strongerbyscience.com/?s=creatine are far more comprehensive, including the famous extremely long podcast episodes they used to do. The one thing this misses is many supplements are tainted, which skews the popular percepti…

> poses no danger to your hair, Last I checked, the only study actually focusing on this is n=38, out of Iran, and has heavy conflict of interest issues (funded by the supplement industry). That's not remotely sufficient to consider this a settled fact.

I feel like you would need to find some correlation between dosing creatine and increased DHT production to find a link between the two.

Creatine is not an anabolic steroid and does not increase testosterone levels, according to Harvard Health, so while there was 1 suspicious study that claimed that creatine increased DHT, that study has afterwards not been able to be replicated, and since creatine does not manipulate hormones but rather energy instead, it seems to as closes a possible to being a settled fact sans the final nail in the coffin.

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