Just do fasting and lose weight. Had high cholesterol and did that lost 20 pounds and my cholesterol went back to normal without any medical intervention
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FDA approves new kind of cholesterol pill
21–30 of 74 posts
Re: FDA approves new kind of cholesterol pill
#22Earlier quoted context omitted.
you didn't read the article did you? Or are you actually here to claim that people with hypercholesterolemia just need to eat better? Do you have the same simplistic ideas about GLP-1's?
For all people? No. For the vast majority of people? Yes. Eat healthy and exercise more.
The dietary impact on cholesterol in the blood is surprisingly low. Looking it up, this source says diet can affect 20-30% of your blood levels [1]. I don’t have a great statistic about exercise, but I’d encourage you to question what you think you know — at the very least I’ll claim you’re mistaken about the importance of dietary impacts on cholesterol, which perhaps should give you pause about your other beliefs
[1] https://my.clevelandclinic.org/health/articles/16867-cholest...
Re: FDA approves new kind of cholesterol pill
#23Just do fasting and lose weight. Had high cholesterol and did that lost 20 pounds and my cholesterol went back to normal without any medical intervention
8% body fat, and I can run more in a day than most people do in a week. I’m taking statins. It’s not always as simple as you seem to assume. As others have said, genetics play role, for one.
Re: FDA approves new kind of cholesterol pill
#24Earlier quoted context omitted.
For all people? No. For the vast majority of people? Yes. Eat healthy and exercise more.
The dietary impact on cholesterol in the blood is surprisingly low. Looking it up, this source says diet can affect 20-30% of your blood levels [1]. I don’t have a great statistic about exercise, but I’d encourage you to question what you think you know — at the very least I’ll claim you’re mistaken about the importance of dietary impacts on cholesterol, which perhaps should give you pause about your other beliefs [1…
Dietary cholesterol has little impact on blood cholesterol. However the post that started this debate mentioned mass loss. And that does have a decent correlation. Go from obese to not obese and the median person's cholesterol will drop quite a bit.
Re: FDA approves new kind of cholesterol pill
#25What is the current state of understanding on high cholesterol as a leading or trailing indicator of poor health? I vaguely remember reading one theory that cholesterol was used by the body to mitigate arterial damage from other causes?
It turns out LDL has different subfractions based on size. Normally, the liver produces large ones which shuttle fat around the bloodstream, lose their payload and shrink then the liver reabsorbs them and the cycle continues.
The problem appears to begin when these LDL molecules hang around for too long. They are damaged by external factors in the bloodstream (eg. glycation due to high blood glucose, oxidation due to fragile polyunsaturated fats) and not recognized anymore for recycling. That's when they can start forming macrophages.
tl;dr LDL by itself is an incorrect measure of cardiovascular risk. Big pharma still profits by selling everyone LDL reducing drugs.
one authentic source: https://www.youtube.com/watch?v=fVLZA0qp-wc
Re: FDA approves new kind of cholesterol pill
#26Earlier quoted context omitted.
The dietary impact on cholesterol in the blood is surprisingly low. Looking it up, this source says diet can affect 20-30% of your blood levels [1]. I don’t have a great statistic about exercise, but I’d encourage you to question what you think you know — at the very least I’ll claim you’re mistaken about the importance of dietary impacts on cholesterol, which perhaps should give you pause about your other beliefs [1…
Dietary cholesterol has little impact on blood cholesterol. However the post that started this debate mentioned mass loss. And that does have a decent correlation. Go from obese to not obese and the median person's cholesterol will drop quite a bit.
It’s possible the comments have changed, but I see nothing in the thread about mass loss. I do agree about weight though — losing weight is largely diet.
> Go from obese to not obese and the median person's cholesterol will drop quite a bit.
This is really interesting, I don’t think I’ve heard that before. Do you have a source you could share?
Edit: this doesn’t necessarily prove you wrong, but this paper argues there’s little correlation between bmi and cholesterol [1]
[1] https://link.springer.com/article/10.1007/s11695-010-0170-7
Re: FDA approves new kind of cholesterol pill
#27What is the current state of understanding on high cholesterol as a leading or trailing indicator of poor health? I vaguely remember reading one theory that cholesterol was used by the body to mitigate arterial damage from other causes?
You should check which part of your body has the most cholesterol.
Re: FDA approves new kind of cholesterol pill
#28What is the current state of understanding on high cholesterol as a leading or trailing indicator of poor health? I vaguely remember reading one theory that cholesterol was used by the body to mitigate arterial damage from other causes?
cholesterol is one of the most crucial molecules for survival. It's used to create and maintain cell membranes, and other critical functions. The vast majority is created by the liver, and there are a lot of regulating signals for how much, which is where usually things go off. Low cholesterol production is an extremely serious condition. The "only" problem with high cholesterol is that it builds up inside artery wal…
> Low cholesterol production is an extremely serious condition.
This is correct, but not in the way you mean it. We know people can effectively produce no LDL cholesterol in their liver and have positive health impacts - these MR studies are a big part of what drove this entire class of cholesterol medications. And the monoclonal antibody versions of PCSK9 inhibitors have shown basically the same results.
Virtually all human cells can produce cholesterol locally de novo, including your brain.
Re: FDA approves new kind of cholesterol pill
#29Just do fasting and lose weight. Had high cholesterol and did that lost 20 pounds and my cholesterol went back to normal without any medical intervention
Are you seriously suggesting to cut into pharma profits?
Re: FDA approves new kind of cholesterol pill
#30One could eat healthy instead of course but hey, the good life .
You will still die you know, no matter your diet. And no god will reward your righteous corpse for eating healthy.