No link between acetaminophen use during pregnancy and adverse birth outcomes

Note that it's also hard on the liver. A lot fatalities due to taking after hangovers, etc: https://www.medicalnewstoday.com/articles/322813 So if you insist, maybe take some NAC.

But apparently, Ibuprofen helps counter the dementia risk:

https://www.aan.com/PressRoom/home/PressRelease/624

I am not not asserting any clever marketing here. I am merely citing public information. Noting all the above, I am confident it's perfectly safe for children and fetuses, and if posing any risk at all, applies strictly to full grown adults. No doubts about child safety have been expressed here.

Re: No link between acetaminophen use during pregnancy and adverse birth outcomes

#4

Post by DANmode » Sat, Jul 18, 2026, 5:48 PM UTC

Now do the study in mutated (MTHR, MTHFR, COMT, others, some combination of them) sample populations.

Re: No link between acetaminophen use during pregnancy and adverse birth outcomes

#5

Post by qsera » Sat, Jul 18, 2026, 5:48 PM UTC

clean chit!

Re: No link between acetaminophen use during pregnancy and adverse birth outcomes

#6

Post by chappy789 » Sat, Jul 18, 2026, 5:54 PM UTC

[flagged]

Re: No link between acetaminophen use during pregnancy and adverse birth outcomes

#7

Post by estearum » Sat, Jul 18, 2026, 6:08 PM UTC

eth0up wrote: post #3

Just for the sake of honest balance, with minimal commentary and no opinions: Acetaminophen and dementia correlation: https://pmc.ncbi.nlm.nih.gov/articles/PMC2877629/ https://www.sciencedirect.com/science/article/abs/pii/S01638... Note that it's also hard on the liver. A lot fatalities due to taking after hangovers, etc: https://www.medicalnewstoday.com/articles/322813 So if you insist, maybe take some NAC. But appa…

The first paper shows no evidence of any effect from Tylenol...? But yeah seems like lots of support for the ibuprofen protective effect, interestingly.

Re: No link between acetaminophen use during pregnancy and adverse birth outcomes

#8

Post by estearum » Sat, Jul 18, 2026, 6:09 PM UTC

DANmode wrote: post #4

Now do the study in mutated (MTHR, MTHFR, COMT, others, some combination of them) sample populations.

Why?

Re: No link between acetaminophen use during pregnancy and adverse birth outcomes

#9

Post by greggsy » Sat, Jul 18, 2026, 6:09 PM UTC

eth0up wrote: post #3

Just for the sake of honest balance, with minimal commentary and no opinions: Acetaminophen and dementia correlation: https://pmc.ncbi.nlm.nih.gov/articles/PMC2877629/ https://www.sciencedirect.com/science/article/abs/pii/S01638... Note that it's also hard on the liver. A lot fatalities due to taking after hangovers, etc: https://www.medicalnewstoday.com/articles/322813 So if you insist, maybe take some NAC. But appa…

The liver toxicity is well known, and overdose is not uncommon.

Re: No link between acetaminophen use during pregnancy and adverse birth outcomes

#10

Post by lokar » Sat, Jul 18, 2026, 6:24 PM UTC

greggsy wrote: post #9

eth0up wrote: post #3

Just for the sake of honest balance, with minimal commentary and no opinions: Acetaminophen and dementia correlation: https://pmc.ncbi.nlm.nih.gov/articles/PMC2877629/ https://www.sciencedirect.com/science/article/abs/pii/S01638... Note that it's also hard on the liver. A lot fatalities due to taking after hangovers, etc: https://www.medicalnewstoday.com/articles/322813 So if you insist, maybe take some NAC. But appa…

The liver toxicity is well known, and overdose is not uncommon.

A better policy fix would be to remove it from multi-drug products. Require it always be the only active ingredient.