191–200 of 427 posts
Magnesium supplementation solved my sleep issues. I have seen many doctors, including sleep specialists, regarding insomnia. They all pointed to one source as the reason for the sleep issues: stress. And they all wanted to put me on prescription sleeping pills. I said no to that. Sleeping pills can cause dependence, and they often treat the symptom rather than the underlying cause. As a software developer, I am used…
Well that sucks, given I have a gene variant related to delayed sleep according to 23andme. Last year I did an experiment of sorts while unemployed for a time and found that if I just slept and woke when tired that my sleep time would naturally recess and eventually "flip" after about a month. My entire life I've wondered why I feel incredibly tired and found waking up so difficult. Turns out that if you follow your…
You are not alone. Recalling from college neuroscience classes and subsequent reading of research, the studies show the ordinary human sleep cycle when unrestrained adds about a half hour per day, so 24.5 hours is 'natural'. Long-term studies with all time cues carefully removed ended up with subjects on a ~50 hour sleep schedule, as in awake 36-38 hours and sleeping 12-14hrs. This is also why it is easier to travel…
Magnesium supplementation solved my sleep issues. I have seen many doctors, including sleep specialists, regarding insomnia. They all pointed to one source as the reason for the sleep issues: stress. And they all wanted to put me on prescription sleeping pills. I said no to that. Sleeping pills can cause dependence, and they often treat the symptom rather than the underlying cause. As a software developer, I am used…
> Sleeping pills can cause dependence, and they often treat the symptom rather than the underlying cause. I found gwern's take on Melatonin interesting: https://gwern.net/melatonin A small excerpt: > One might object that they do not wish to tamper with their natural sleep, even if melatonin is a normally-secreted hormone. > Sad to say, I would point out to such readers that they are already profoundly tampering with…
> There are few to no side-effects to melatonin use in adults (there is uncertainty about the risks & benefits in children & adolescents28), and it is not addictive or habit-forming like caffeine is. The usual dose for a night is 0.5-3 mg and I take 1.5mg [29]; my dose is highly likely to be too high. High doses may well be responsible for why some people try melatonin and report that it does nothing or hurts them, since in one study, the best dose for old people was 10x smaller (0.1mg or 0.3mg) and for one blind person, 0.5mg [30 31 32] . Zhdanova et al 1996 found 0.3mg & 1.0mg to affect sleep onset similarly. A study of delayed-release melatonin found with their high dose of 4mg (but not 0.4mg) elevated melatonin levels 10 hours after bedtime ( Gooneratne et al 2011) - potentially interfering with waking time.
It is difficult to find doses as small as 1mg sublingual (dissolve under the tongue) in my area. Everyone is trying to sell you 5-30mg chewables. And, I expect everyone is buying them under the assumption that more is better. But, here it explicitly is not.
The way melatonin works well for me is to wait until I'm already settled into bed and should be asleep, but I'm not. Do a couple body scans to relax for real. Try to think about something mindless. Then if I'm still awake, pop 1mg under my tongue. I'll usually wake in the morning with half of it drooled on my pillow :P
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Holy Dunning–Kruger effect... As a software developer, I am a much better doctor than actual trained doctors, and am definitely immune to any placebo effects.
I don’t know anything about the specifics of this case. I do know there are lots of bad doctors. Doctors routinely make mistakes or overlook things, especially relatively trivial things like this. I don’t know what people think you learn in medical school that makes you an infallible source of health knowledge.
The problem is not with evidence-based medicine itself, but with how the evidence is generated. The gold standard of medical evidence--a large, randomized, double-blind clinical trial--is extraordinarily expensive. In practice, much of this research is funded by private industry, which must have a reasonable expectation of earning a return on its investment. That naturally directs research toward treatments that can be patented, commercialized, and sold at a profit.
This creates a structural blind spot. Many naturally occurring compounds cannot be patented in their natural form, making it difficult to justify the enormous cost of conducting the kind of trials that modern medicine demands. As a result, potentially useful natural therapies often remain under-studied, not because they have been proven ineffective, but because the economic incentives to investigate them are weak.
This is the reason your doctor is much more likely prescribe Ambien CR than to suggest trying magnesium supplements.
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I've tried both Magnesium Glyconate and Magnesium L-Threonate and both have helped my sleep, Magnesium Citrate did very little. Which makes sense, the latter is known to not be absorbed very well. I've not noticed any significant difference between the other two.
Magnesium citrate works well for constipation, IME.
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> Sleeping pills can cause dependence, and they often treat the symptom rather than the underlying cause. I found gwern's take on Melatonin interesting: https://gwern.net/melatonin A small excerpt: > One might object that they do not wish to tamper with their natural sleep, even if melatonin is a normally-secreted hormone. > Sad to say, I would point out to such readers that they are already profoundly tampering with…
The comment above just said “sleeping pills” which is ambiguous. Melatonin is an OTC supplement. True “sleeping pills” are usually controlled substances and few doctors would prescribe them as first-line options for a patient who shows up with first time complaints of sleep problems. They won’t be prescribed long-term either. The part of the post that says doctors (plural) tried to prescribe the pills makes me think…
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This. And maybe anecdotal, but my experience of people who have used melatonin is that they sleep very deeply, but for a shorter amount of time. But likely they will wake up after around 6/7 hours sleep, rather than the recommended 8 hours of sleep. And once woken up, it's very hard to go back to sleep.
> rather than the recommended 8 hours of sleep for people getting 7 hours of sleep you're good. Improve your sleep hygiene, ok, but artificial interventions to get 8 may not be worth it for you.
Magnesium supplementation solved my sleep issues. I have seen many doctors, including sleep specialists, regarding insomnia. They all pointed to one source as the reason for the sleep issues: stress. And they all wanted to put me on prescription sleeping pills. I said no to that. Sleeping pills can cause dependence, and they often treat the symptom rather than the underlying cause. As a software developer, I am used…
Holy Dunning–Kruger effect... As a software developer, I am a much better doctor than actual trained doctors, and am definitely immune to any placebo effects.
Do you know they’re wrong? Please don’t invoke Dunning Kruger like this, it’s cliché and also wrong to do. There’s no indicator for whatever it is Dunning & Kruger showed, you cannot know if it applies to a single person. Their main plot showed a positive correlation between confidence and competence. Their paper has problems, their methodology has been rightly questioned, and some attempts to reproduce have failed. Plus keep in mind that, ironically, for people who are intimately familiar with the debate over DK, using it to essentially name-call someone backfires and has the opposite of the intended effect, it makes the name caller look confidently ignorant.
Magnesium supplementation solved my sleep issues. I have seen many doctors, including sleep specialists, regarding insomnia. They all pointed to one source as the reason for the sleep issues: stress. And they all wanted to put me on prescription sleeping pills. I said no to that. Sleeping pills can cause dependence, and they often treat the symptom rather than the underlying cause. As a software developer, I am used…
I did it recently and found out basically all my b vitamins were in the toilet along with my vitamin D level. I started taking a b complex vitamin and D3 supplement and found immediate improvements to brain fog and exhaustion.