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The shingles vaccine may reduce the risk of dementia

economist.com

181–190 of 234 posts

Re: The shingles vaccine may reduce the risk of dementia

#181

Earlier quoted context omitted.

Not common knowledge, but should be in this day and age. For example, someone who worked in daycare and often got sick with the flu or similar, has a higher risk of dementia (statistically-speaking). When I learned it, it was in the context of the influenza and similar common viruses. It's actually more nuanced than that. If you want to read more: https://www.openevidence.com/ask/bccc3cc2-e15d-4fb0-a0c5-16f...

As far as I know you're overstating what is known. There was a study that showed that people who had severe influenza (they were hospitalized) were 3 times more likely to develop dementia. And there are mouse models that show that frequency respiratory virus infections can increase may contribute to brain aging (in mice). >someone who worked in daycare and often got sick with the flu or similar, has a higher risk of…

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Re: The shingles vaccine may reduce the risk of dementia

#183

Earlier quoted context omitted.

Not common knowledge, but should be in this day and age. For example, someone who worked in daycare and often got sick with the flu or similar, has a higher risk of dementia (statistically-speaking). When I learned it, it was in the context of the influenza and similar common viruses. It's actually more nuanced than that. If you want to read more: https://www.openevidence.com/ask/bccc3cc2-e15d-4fb0-a0c5-16f...

As far as I know you're overstating what is known. There was a study that showed that people who had severe influenza (they were hospitalized) were 3 times more likely to develop dementia. And there are mouse models that show that frequency respiratory virus infections can increase may contribute to brain aging (in mice). >someone who worked in daycare and often got sick with the flu or similar, has a higher risk of…

I'm extrapolating some. But pediatricians have higher rates of dementia compared to their counterparts (physicians have lower dementia in general): https://link.springer.com/article/10.1007/s40520-019-01278-4

Re: The shingles vaccine may reduce the risk of dementia

#184

If you haven't seen the chart from the UK study, I highly recommend checking it out: https://erictopol.substack.com/p/the-shingles-vaccine-and-re... When the vaccine came out in the UK, they included a hard age cutoff: Above a certain age, you weren't eligible. Below that age, you were eligible. They looked at the probability of a dementia diagnosis over the 7 years after the vaccine was introduced. People who were b…

So much of neurodegeneration has turned out to be the effects of latent viruses in the body. HSV-1 is correlated with developing dementia along with many respiratory viruses.

Re: The shingles vaccine may reduce the risk of dementia

#185

I know quite a few people who got shingles in their early 20s. One of their doctors didn’t believe she had shingles until the blisters formed. The vaccine can definitely help those younger than 50, dementia benefits or not. Some of them have permanent nerve damage after getting shingles.

My brother had it when he was 17

I had it at 14

Re: The shingles vaccine may reduce the risk of dementia

#186

Earlier quoted context omitted.

You can get basically any medication or vaccination you want in the US as long as you can find a doctor to write the prescription. We even have anabolic steroids that were approved for muscle wasting in cancer patients, but if you can find a doctor willing to write the prescription and a pharmacy that won’t question it, anyone can have pharmacy grade Anavar for the gym, completely legal. In theory the doctor writing…

> You can get basically any medication or vaccination you want in the US as long as you can find a doctor to write the prescription. Is that not usually true in other countries?

In some countries, getting that prescription is much harder (unless you have the medical condition the medicine is intended/licensed for)

Re: The shingles vaccine may reduce the risk of dementia

#187

If you haven't seen the chart from the UK study, I highly recommend checking it out: https://erictopol.substack.com/p/the-shingles-vaccine-and-re... When the vaccine came out in the UK, they included a hard age cutoff: Above a certain age, you weren't eligible. Below that age, you were eligible. They looked at the probability of a dementia diagnosis over the 7 years after the vaccine was introduced. People who were b…

Looks like there's no difference in men, but a huge difference in women? What a weird situation.

Re: The shingles vaccine may reduce the risk of dementia

#189

Unfortunately this is a spurious finding. See this presentation: https://youtu.be/qlTnnQytOJ0 The mechanism is that people with the shingles vaccine are less likely to visit the hospital (because they don't get shingles). Because they have fewer hospital visits they are less likely to receive an incidental diagnosis of dementia from a hospital.

are there that many instances of mild dementia where a lack of diagnosis remains a lack?

Well it does tend to happen late in life where other health issues could take you out before the dementia gets noticeable beyond usual senility.

Re: The shingles vaccine may reduce the risk of dementia

#190
post #169

Earlier quoted context omitted.

This isn't common knowledge. This is something people (non-experts) are starting to infer, because we're seeing it with Long COVID - https://news.ycombinator.com/item?id=48877214 - but there's no reason to think this is something special about SARS-CoV-2 - it could just as well happen with all viral infections but we weren't looking. It reminds me that we didn't look at vaccine efficacy at the individual level until…

From a legal perspective, if the injection does not provide 100% immunity (when used as directed), then it cannot be called a vaccine, instead it is a therapeutic treatment. Because courts of law have recognized covid mRNA injections as therapeutic treatments, they cannot be mandated.

That sounds like nonsense. Most vaccines do not provide 100% immunity.
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