Wow mucosal innervation was around half in long covid patients - that's super worrying and would have nasty symptoms in practice. The findings also support the hypothesis that SARS-CoV-2 may cause structural nerve damage, which is perhaps the even bigger worry. :(
Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
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Re: Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
#22Re: Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
#23Earlier quoted context omitted.
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Problem with those conditions and long COVID and CFS are generally similar: No really reliable guaranteed test for most of them, just a series of symptomatic diagnoses and years of ruling out conditions. No offense, but while some people might be full of crap, you sound really insensitive.
When your doctor says that you're wrong, do you accept his advice or tell him he should be more like Dale Carnegie?
Re: Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
#24Is there a test for long covid?
There's no such thing as "long COVID" specifically. Any serious viral infection has the potential to cause sequalae in susceptible patients for reasons that are still not well understood. Some of those are detectible in lab tests to an extent but there's no single clear diagnostic test.
they are also distinct from other conditions like ME/CFS or other sequelae although they may share overlapping symptoms. A lot of research is going into different PAIS post acute infection syndromes
Re: Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
#25Is there a test for long covid?
Re: Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
#26Earlier quoted context omitted.
Problem with those conditions and long COVID and CFS are generally similar: No really reliable guaranteed test for most of them, just a series of symptomatic diagnoses and years of ruling out conditions. No offense, but while some people might be full of crap, you sound really insensitive.
If you suppose it's all malarkey and conjecture, what is the problem? When your doctor says that you're wrong, do you accept his advice or tell him he should be more like Dale Carnegie?
FWIW, if my doctor were unfriendly enough, though, I might do that also.
Re: Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
#27hopefully we will get somewhere with these studies. The lack of solid research on a disease that affects millions (likely a good percentage undiagnosed) is really tough for patients - and myself really, as I've found i likely suffer from this. Finding out about autonomic dysfunction and small fiber neuropathy as I researched my own fatigue and finding out I likely have this has been very challenging.
Please don't do this. It's the medical equivalent of copy/pasting shit you don't understand from Stack Overflow.
Go see a doctor who has a degree and training.
Re: Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
#288 people as the entire control group... yeah I'd say "may" is the operative word in the title. My takeaway from long covid is that it's probably as severe as the much more deadly pandemic of the Spanish Flu. Considering there's now a newfound interest in "long flu", I think a spotlight has now been placed on the impact of severe respiratory illness. Whether that illness be covid or one of the any other respiratory il…
Yeah, twelve patients and eight in the control group isn't really a study.
Re: Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
#29Is there a test for long covid?
Think of AIDS before the immune system dysfunction was found. That's where we are with Long Covid. One cause, a myriad of apparently unrelated effects--that's not how biology tends to work. Rather, there's something deeper we haven't found. And we certainly can't test for what we haven't found.
Re: Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19
#30Earlier quoted context omitted.
Yeah, twelve patients and eight in the control group isn't really a study.
is a small proof of concept study not a study anymore? gastric biopsies aren’t exactly easy to obtain at scale.