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How to sequence your own DNA at home

bradleywoolf.com

41–50 of 161 posts

Re: How to sequence your own DNA at home

#41
post #37

Earlier quoted context omitted.

That’s a really clever idea, I would definitely pay for that in the right circumstances. Now that I think about it - could you just pour some sort of biodegradable broad-spectrum herbicide down the drain to get the same effect for cheaper?

This is precisely what I do each year with a product designed for this exact purpose. $8+shipping gets me enough for my annual pipe maintenance. It's even the special kind because I have clay pipes. I don't wasn't to kill parents idea. It's neat, and Im sure there's use cases that my solution doesn't meet

I hope yours keeps working for you. I flushed a lot of blue crystals, but the plant was not deterred.

Re: How to sequence your own DNA at home

#42
Bringing everything to your doorstep and everything at your feet and everything near your fingertips is just what all industries are trying to accomplice. The cartoon Animation Wall-E has scenes in it where they show obese humans doing everything through a screen though notice their legs and feet and it's as if they've mutated to a point where they aren't able to walk anymore and all their transport is through a hovering chair cum bed.

Re: How to sequence your own DNA at home

#43
post #39

I'm too afraid I would learn something awful about myself.

Unfortunately you’d have no power to correct it. Even if such a thing were possible. I hope that changes.

Are you talking about time travel? I don't think that would help.

Re: How to sequence your own DNA at home

#44

I like the privacy conscious aspects. Apart from the obvious issue of "run it through Claude" how many of those referenced analysis tools are entirely open source or at least run locally? Would have liked to see that in the article.

At a quick glance, they all seem to have published their source code and they do run locally.

Re: How to sequence your own DNA at home

#45

Reminds me of the Gloing Plant Project. I never got my glowing flower but would have settled for the instruction manual, also never created :( https://en.wikipedia.org/wiki/Glowing_Plant_project By the by, can't seen to bring up the actual site linked on this post.

You can get one here, you'll have to wait until next year though: https://light.bio/

Re: How to sequence your own DNA at home

#46
post #39

Earlier quoted context omitted.

Unfortunately you’d have no power to correct it. Even if such a thing were possible. I hope that changes.

Are you talking about time travel? I don't think that would help.

More like genome editing.

Re: How to sequence your own DNA at home

#47
post #15
post #8

Earlier quoted context omitted.

If it's an US-based lab, aren't they subject to CLIA with all its retention requirements? For $7.5k+ you get a guaranteed privacy (as other comments suggest, other properties may vary, but at least the data never leaves your home).

I suspect there is a deep sequencing service that is non CLIA and cheap. True. they may not be trustworthy with the data. That said, there are steps here where the data is put into Claude. Do we trust that ?

That's another vector, and everyone considers separately. But at least here one can - hypothetically - have a BAA and zero-retention agreement with Anthropic. Which means they have moderately strong incentives to wipe your data after a fairly short while. CLIA, if I don't misremember, mandates a few years at minimum.

Re: How to sequence your own DNA at home

#48

Bringing everything to your doorstep and everything at your feet and everything near your fingertips is just what all industries are trying to accomplice. The cartoon Animation Wall-E has scenes in it where they show obese humans doing everything through a screen though notice their legs and feet and it's as if they've mutated to a point where they aren't able to walk anymore and all their transport is through a hove…

I watched wall-e in theater, and when that scene came on, i remember muttering 'what bs'; since then, i recall that scene every time i see a situation of 'convenience at all costs'; metaphorically they were pretty accurate even after discounting ozempic influence;

Re: How to sequence your own DNA at home

#49

> This is intended to be read by AI- please just copy and paste the URL of this and have ChatGPT walk you through it. If you have AR glasses, even better, since the AI can walk you through the whole protocol. What kind of magic is going on here, am I missing something?

I feel it's actually kind of smart. Most people won't be reading the blog post themselves, they'd ask GPT to understand the text and fetch the summary or whatever is relevant to them. The author has directly made the resource such that it is optimised for the output after that mostly-everyone-would-do-this step.
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