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Using precision editing to study human embryo development shows master gene

cam.ac.uk

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Re: Using precision editing to study human embryo development shows master gene

#3

Post by bpodgursky »

ape4 wrote: post #2

I wonder what the regulations are for this sort of work

In the US it's legal-sorta but the NIH can't fund it and the FDA is not allowed to approve treatments based on it. So someone could do it in a research setting but there's not a pathway to market in the US (in practice people will do the first ones in a friendly legal climate like Peru).

Re: Using precision editing to study human embryo development shows master gene

#5

Post by kens »

ape4 wrote: post #2

I wonder what the regulations are for this sort of work

The short answer is the "14-day" rule, which doesn't allow development of the embryo beyond 14 days. The article gives specifics under the heading "Ethical and legal compliance"

Re: Using precision editing to study human embryo development shows master gene

#6

Post by bonsai_spool »

bpodgursky wrote: post #3
ape4 wrote: post #2

I wonder what the regulations are for this sort of work

In the US it's legal-sorta but the NIH can't fund it and the FDA is not allowed to approve treatments based on it. So someone could do it in a research setting but there's not a pathway to market in the US (in practice people will do the first ones in a friendly legal climate like Peru).

> In the US it's legal-sorta but the NIH can't fund it and the FDA is not allowed to approve treatments based on it

What references are you following? Haven't heard this before.

Re: Using precision editing to study human embryo development shows master gene

#9

Post by MichaelZuo »

Does anyone know why such a fundamental gene would have such different behaviours between mammals?

> In previous mouse studies, loss of NANOG disrupted both the epiblast and the yolk sac - a tissue that supports the developing embryo. In this human embryo study, loss of NANOG primarily affected the epiblast, the future body-forming line of cells.

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