IMO If you're into tech and still use Chrome*, that's on you. If you are not, you probably don't really care unless you need extra space on your PC. *Except in your job, since you probably obligated to use.
Switched from firefox few months ago, I don't like google, but firefox has only few percent of market share currenly, many pages simply do not work properly with it, plus it has bugs on macos (like onmousover stuff), which simply make it unusable. Safari is fine, but also many websites (which sometimes you need to use like banking or gov) are not tested on it. The overall browsers situation is less than ideal.
I use firefox on mac and I have simply no clue what you're talking about. Tons of people use firefox on mac quite successfully...
The only page that I know of that doesn't work is google earth - it doesn't work on linux either. (Technically it does, just incredibly laggy compared to chrome)
I can't think of a single macos specific bug. Or a single mouse over related bug.