For me, cannabis causes anxiety, and it’s pretty well established that anybody with anxiety or bipolar or schizophrenia should not be using cannabis because it can make these much worse. I don’t suffer anxiety anymore, but there’s plenty of scientific evidence about the relationship between anxiety and cannabis use.
Cannabis users face substantially higher risk of heart attack (2025)
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Re: Cannabis users face substantially higher risk of heart attack (2025)
#12Literally no mention of ROA. It matters whether they smoke plant matter, vape, use it orally, etc. This, combined with their inability to account for a number of other factors such as tobacco use, makes this study literally useless. Earned a flag from me.
Re: Cannabis users face substantially higher risk of heart attack (2025)
#13Would be nice to know how much of a role a sedentary lifestyle plays in it or if it puts everyone at risk regardless of other habits. Maybe this just means you need to do cardio several times a week to keep using THC.
FWIW, I've smoked cannabis daily for maybe 15 years, I'm not exactly sedentary (have dogs, a partner and like to (lazily) swim in the sea) but generally don't exercise. Visited a cardiologist like two months ago and have perfectly fine heart despite the smoking.
Anecdotal of course, many could probably bring up counter-stories too, but I do think you bring up a good point, it seems to me a completely sedentary lifestyle seems to be way more destructive to your health than moderate usage of various drugs and/or eating habits. People who just walk a bit daily already seem way healthier and happier than peers in their same age.
Re: Cannabis users face substantially higher risk of heart attack (2025)
#14> researchers were unable to account for several potential confounding factors including the duration and amount of cannabis use or the use of tobacco or other drugs. Personally I'd wager a bet it's the tobacco and/or smoking that is the harmful part, but it kind of dumbfounds me they failed to account for "details" like "duration and amount of cannabis use", that feels like a very vital thing to control for. Nothing…
Do you smoke?
Literally just wrote about that: https://news.ycombinator.com/item?id=48794178
> I've smoked cannabis daily for maybe 15 years [...] Visited a cardiologist like two months ago and have perfectly fine heart despite the smoking.
Re: Cannabis users face substantially higher risk of heart attack (2025)
#15> researchers were unable to account for several potential confounding factors including the duration and amount of cannabis use or the use of tobacco or other drugs. Personally I'd wager a bet it's the tobacco and/or smoking that is the harmful part, but it kind of dumbfounds me they failed to account for "details" like "duration and amount of cannabis use", that feels like a very vital thing to control for. Nothing…
Exactly. Being unable to account for this covariate (tobacco use) pretty much invalidates this analysis. The odds ratio for tobacco use is basically the same (3x).
Also, title needs a 2025.
Re: Cannabis users face substantially higher risk of heart attack (2025)
#16Literally no mention of ROA. It matters whether they smoke plant matter, vape, use it orally, etc. This, combined with their inability to account for a number of other factors such as tobacco use, makes this study literally useless. Earned a flag from me.
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Re: Cannabis users face substantially higher risk of heart attack (2025)
#17> researchers were unable to account for several potential confounding factors including the duration and amount of cannabis use or the use of tobacco or other drugs. Personally I'd wager a bet it's the tobacco and/or smoking that is the harmful part, but it kind of dumbfounds me they failed to account for "details" like "duration and amount of cannabis use", that feels like a very vital thing to control for. Nothing…
> Nothing is good for you in too great amounts, even water
Re: Cannabis users face substantially higher risk of heart attack (2025)
#18I’m annoyed by the bifurcated regulatory regime Substances approved by the FDA are done based on specific treatments, with multiple trials and approval per use case Substances declared scheduled are illegal by the substance itself, instead of per use case paradoxically because there is no FDA approved use case and almost no way to get one meaning that places in the US that diverge in legality and are ignored by the f…
The US government is now in thrall to the Kratom industry though isn't it? No reason to expect any logical consistency from them.
(Literally the person currently responsible for the branch of government that keeps illegal drugs out of the country is an investor in a Kratom company)
Re: Cannabis users face substantially higher risk of heart attack (2025)
#19> researchers were unable to account for several potential confounding factors including the duration and amount of cannabis use or the use of tobacco or other drugs. Personally I'd wager a bet it's the tobacco and/or smoking that is the harmful part, but it kind of dumbfounds me they failed to account for "details" like "duration and amount of cannabis use", that feels like a very vital thing to control for. Nothing…
Exactly. Being unable to account for this covariate (tobacco use) pretty much invalidates this analysis. The odds ratio for tobacco use is basically the same (3x). Also, title needs a 2025.
This article refers to two studies. The retrospective study of 4.6 million people did account for tobacco use.
> The findings are from a retrospective study of over 4.6 million people published in JACC Advances and a meta-analysis of 12 previously published studies being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).
> Kamel and his team conducted the retrospective study using data from TriNetX, a global health research network that provides access to electronic medical records. Their findings indicate that over an average follow-up of over three years, cannabis users had more than a sixfold increased risk of heart attack, fourfold increased risk of ischemic stroke, twofold increased risk of heart failure and threefold increased risk of cardiovascular death, heart attack or stroke. All study participants were younger than age 50 and free of significant cardiovascular comorbidities at baseline, with blood pressure and low-density lipoprotein (LDL) cholesterol levels within a healthy range and no diabetes, tobacco use or prior coronary artery disease.
Re: Cannabis users face substantially higher risk of heart attack (2025)
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