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Cannabis users face substantially higher risk of heart attack (2025)

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Re: Cannabis users face substantially higher risk of heart attack (2025)

#3

It’s starting to look like THC ( found in gummies, too ) causes vascular problems.

Before we got Ozempic there was great hope for

https://en.wikipedia.org/wiki/Rimonabant

which blocks the receptor that THC binds to and led to weight loss and further improvements of the “metabolic syndrome” beyond weight loss alone. Unfortunately it caused major depression in some people including suicide.

So looking at it that way it would be no surprise that cannabis causes weight gain and metabolic syndrome and in fact my experience is that if I am using cannabis I get a few kg. I think that is the THC and on top of that if you are smoking you are inhaling small particles that turn your blood into sludge (e.g. your blood is a “complex fluid” with cells in it that can be damaged) and doing damage to your lungs and capillaries and promoting inflammation and all that.

Re: Cannabis users face substantially higher risk of heart attack (2025)

#5
> researchers were unable to account for several potential confounding factors including the duration and amount of cannabis use or the use of tobacco or other drugs.

Personally I'd wager a bet it's the tobacco and/or smoking that is the harmful part, but it kind of dumbfounds me they failed to account for "details" like "duration and amount of cannabis use", that feels like a very vital thing to control for. Nothing is good for you in too great amounts, even water, so not taking that into account seems to not really give reliable and trustworthy results.

Re: Cannabis users face substantially higher risk of heart attack (2025)

#6
I’m annoyed by the bifurcated regulatory regime

Substances approved by the FDA are done based on specific treatments, with multiple trials and approval per use case

Substances declared scheduled are illegal by the substance itself, instead of per use case

paradoxically because there is no FDA approved use case and almost no way to get one

meaning that places in the US that diverge in legality and are ignored by the federal government have done so without any clinical trial, which would be some level of peer reviewed objective information by use case instead of the whole substance

we can’t even get a simple list of side effects, or a disclaimer about what kind of users shouldn’t use it

only anecdotes

that annoys me and it’s not just about weed

Re: Cannabis users face substantially higher risk of heart attack (2025)

#8
Not really related, but the other thing I found out recently that cannabis can cause is the worst panic attack I have ever experienced: a DPDR (derealization / depersonalization) panic attack. I’ve had regular panic attacks before. I get one a year, roughly, where I get essentially heart attack symptoms. But this was something else. It felt like something was truly, irrevocably broken with my mind and I couldn’t even describe what. Utterly terrifying. I was a heavy user but dropped it the next day.

Re: Cannabis users face substantially higher risk of heart attack (2025)

#9

> researchers were unable to account for several potential confounding factors including the duration and amount of cannabis use or the use of tobacco or other drugs. Personally I'd wager a bet it's the tobacco and/or smoking that is the harmful part, but it kind of dumbfounds me they failed to account for "details" like "duration and amount of cannabis use", that feels like a very vital thing to control for. Nothing…

I tried to look up the source article, but there doesn’t seem to be any mention of consumption of edibles versus smoking.

Re: Cannabis users face substantially higher risk of heart attack (2025)

#10

> researchers were unable to account for several potential confounding factors including the duration and amount of cannabis use or the use of tobacco or other drugs. Personally I'd wager a bet it's the tobacco and/or smoking that is the harmful part, but it kind of dumbfounds me they failed to account for "details" like "duration and amount of cannabis use", that feels like a very vital thing to control for. Nothing…

Do you smoke?
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